Center for Computational and Integrative Biology

The Massachusetts General Hospital Center for Computational and Integrative Biology (CCIB), led by Ramnik Xavier, MD, PhD, is conducting research into diverse topics such as the origins of life, the mechanisms of host-pathogen interactions in plants and model organisms, the relationship between artherosclerosis and inflammatory response in vertebrates, and identifying indications of adverse outcomes (principally sepsis and its sequelae) in individuals being treated for trauma

Our Mission

The Center for Computational and Integrative Biology at Massachusetts General Hospital supports investigators at the hospital and across Boston through a variety of autonomous cores that provide services in DNA sequencing, oligonucleotide synthesis, microarray analysis and research laboratory automation.

The faculty’s interests include the origins of life, the mechanisms of host-pathogen interactions in plants and model organisms, the relationship between atherosclerosis and inflammatory responses in vertebrates and the collection and analysis of comprehensive measures of physiology in an attempt to understand the harbingers of adverse outcomes in individuals treated for trauma.