Department of Neurology
Grand Rounds Lecture Series
In addition to the main Neurology Grand Rounds series, the Department of Neurology is proud to host a variety of specialized lecture and symposium events, including Global Health Neurology Grand Rounds, the Multicultural Alzheimer's Prevention Project Grand Rounds and the McCance Center Lecture Series.
Neurology Grand Rounds Recordings
This timely and informative seminar series addresses major topics in neurology, including stroke, epilepsy, and the neurological complications of COVID-19. For details about Grand Rounds and Mass General Brigham Continuing Professional Development, please visit the Neurology Grand Rounds course page. Selected lecture recordings are shared here.Thursday, November 14, 2024: Blood-Based Biomarkers for Alzheimer’s Disease and Related Disorders in Clinical Research and Clinical Practice
Steven E. Arnold, MD
Thursday, October 31, 2024: Preventing Parkinson’s
Michael A. Schwarzschild, MD, PhD
Thursday, October 17, 2024: Genetic Therapies for Severe Neurovascular Disorders: From Bedside to Bench and Back Again
Patricia L. Musolino, MD, PhD
Thursday, September 5, 2024: What Can Neurology Learn from Functional Neurological Disorder: Clinical, Neurobiological & Programmatic Insights
David L. Perez, MD
Thursday, July 25, 2024: Neurofibromatosis Type 1: Updates on Diagnosis and Treatment
Justin T. Jordan, MD, MPH, FAAN
Thursday, June 27, 2024: Artificial Intelligence and Clinical Neurology
James Hillis, MBBS, DPhil
Thursday, May 30, 2024: The Journey of Endovascular Therapy for Acute Stroke: Past, Present, and Future
Raul G. Nogueira, MD, FAHA, FSVIN
Thursday, May 23, 2024: MTT Lecture: Music, Medicine, and Machine Learning
Tina Tallon, PhD
Thursday, May 16, 2024: Lessons Learned in Industry and Applications to Academia: Translational Neuroscience Fellowships at MGH
Denis Balaban, MD
Thursday, May 9, 2024: Residency Certificates Presentation 2024
- Design, Implementation and Evaluation of a Novel Headache Curriculum for MGB Neurology Residents
Minali Nigam, MD - Navigating uncharted waters - autism education research and advocacy in Uganda
Franziska Hoche, MD - Mechanical Thrombectomy for Acute Ischemic Stroke in Patients with Severe Baseline Disability: A Single-Center Experience at Massachusetts General Hospital
Amine Awad, MD
Thursday, March 28, 2024: Basic, Translational and Clinical Neuromodulation in Epilepsy and Beyond
Sydney Cash, MD, PhD
Thursday, March 14, 2024: Pediatric Disorder Consciousness: Neuroprotection and Neuroprognostication
Mark Wainwright, MD, PhD
Thursday, February 22, 2024: Redefining Precision in Precision Medicine: Learning from Gene Therapy Trials
Florian Eichler, MD
Barlow Lecture - Thursday, February 15, 2024: Stroke in Childhood - Progress and Prospects
Presented by Rebacca Ichord, MD from Children's Hospital of Philadelphia
Thursday, February 8, 2024: A Framework for Precision Stroke Neurorehabilitation
Presented by David J. Lin, MD
Thursday, January 18, 2024: Spinal Muscular Atrophy Across the Year
Presented by Basil Darras, MD
Thursday, January 11, 2024: NEJM Case Records of the MGH - A 64 year old woman with sudden onset of the worst headache of her life
Meridale Baggett, MD / Jonathan Edlow, MD, FACEP / Gabriella DiCarlo, MD, PhD / Javier Romero, MD, FAHA / Aneesh Singhal, MD
Thursday, December 14, 2023: From Genes to Therapies for the Hereditary Spastic Paraplegias
Presented by Craig D. Blackstone, MD, PhD
Thursday, November 30, 2023: Sports Neurology - Much More Than Concussion
Presented by Claus Reinsberger, MD, PhD
Thursday, November 16, 2023: Cerebellar Function and Neuropsychiatry: Implications for the Developing Brain
Presented by Jeremy Schmahmann, MD
Thursday, October 26, 2023: Case Records of the MGH - A 58-year-old woman with 16 months of recurrent confusion and evolving changes on magnetic resonance imaging of the brain
Meridale Baggett, MD / Jenny Linnoila, MD, PhD / Lena Liu, MD / Otto Rapalino, MD / Maria Martinez-Lage Alvarez, MD / Melissa Walker, MD, PhD
Thursday, October 19, 2023: Preventing Dementia by Preventing Stroke: Evidence from Epidemiology
Rebecca Gottesman, MD talks about the cognitive impacts of stroke and cerebrovascular disease.
Thursday, September 21, 2023: Challenges in Perinatal Computational Neuroimaging in the In Vivo and Ex Vivo Domains
Dr. Zollei’s presentation focuses on her work related to various neuroimaging solutions related to human brain development. Her research interest includes but is not limited to algorithm development; brain; brainstem; cerebellum; cerebrum; consciousness; diffusion magnetic resonance imaging; diffusion weighted image alignment; human brain development; image processing computer-assisted; imaging three-dimensional; infant; infant newborn; longitudinal analysis; mri; multimodal neuroimaging; pattern recognition automated and postmortem brain tissue.
Thursday, September 7, 2023: Cerebral Small Vessel Diseases and Atrial Fibrillation - The New Heart & Brain Connection
Dr. M. Edip Gurol, M.D, Associate Professor of Neurology at MGH and stroke neurologist, speaks about the relationship between cerebral small vessel disease and atrial fibrillation.
Thursday, July 27, 2023: Stress Signaling in Glioblastoma Pathogenesis, Metabolism, and Response to Therapy
Dr. Christian Badr talks about the impact of stress signaling in Glioblastoma stem cells and how these cells can hijack the stress response to promote tumor growth by enhancing lipid metabolism and acquiring therapeutic resistance.
Thursday, June 8, 2023: Drivers and Determinants of Post-Stroke Cognition and Brain Volume
Dr. Amy Brodtmann, Professor and Lead for the Cognitive Health Initiative at Monash University in Australia, speaks about drivers and determinants of post-stroke cognition.
Thursday, May 18, 2023: Fetal Neurology - Overview and Current Practice
Dr. Sonika Agarwal presents an overview of fetal neurology and current practice including a discussion of challenges in prenatal counseling of common fetal neurologic disorders/malformations and their outcomes, a presentation of work of the Fetal Neurology Consortium to advance the field, and an overview of the global experience in maternal-fetal medicine in relation to fetal neurology.
Thursday, May 9, 2023: MGB Neurology Grand Round/Residency Certificates
Jonathan Duskin MD speaks about the relationship between body mass index and intracerebral hemorrhage severity; Lena Liu, MD reviews EEG teaching via social media platforms and an online database in collaboration with EEG Master; Deena Godfrey, MD presents medication reconciliation quality improvement project completed through the neurology certificate program.
Thursday, April 20, 2023: The Golden Age of Neuroscience
Walter Koroshetz, MD, Director of the National Insitute of Neurological Disorders and Stroke (NINDS), gives an inspiring Charles Miller Fisher Visiting Professorship Lecture faculty, staff and alumni on the inspiration of C. Miller Fisher and the NINDS's role in advancing the field of neurology.
Hung CPC (3/16/23)
Thursday, March 16, 2023: NEJM Case Records of the MGH - A 79-Year-Old Man with Left-Sided Involuntary Movements
Meridale V. Baggett, MD, Albert Hung, MD, PhD, Carrie Chui, MD, Rajiv Gupta, PhD, MD, Scott Silverman, MD, Caroline F. Hilburn, MD
Thursday, February 9, 2023: Neurodevelopmental Origin of Childhood Central Nervous System Tumors
Scott L. Pomeroy, MD, PhD, Bronson Crothers Professor of Neurology, Harvard Medical School, Chair, Department of Neurology and Neurologist-in-Chief, Boston Children’s Hospital Associate Member, Broad Institute of MIT and Harvard, gives an overview of neurodevelopmental origin of childhood brain tumors with a focus on molecular subtypes and genetic variation.
Thursday, January 19, 2023: Using Digital Data to Quantify Behavior and Function in ALS and Hasten Drug Development
Dr. James Berry, MD, MPH, the Winthrop Family Scholar in ALS Sciences, Averill Healey Endowed Chair in ALS, Associate Chief for Neurotherapeutics, and Chief of the Division of ALS and Motor Neuron Diseases at MGH, discusses using Digital Data to Quantify Behavior and Function in ALS and Hasten Drug Development.
Previous Lectures
Thursday, December 15, 2022: Neurology Grand Rounds with Dr. Bradley Hyman, MD, PhD
Dr. Bradley Hyman, MD, PhD, the John B. Penny Professor of Neurology, Co-Vice Chair for Research in Neurology,and Director of the Massachusetts Alzheimer Disease Research Center at Massachusetts General Hospital, discusses the molecular underpinnings correlating with clinical heterogeneity in Alzheimer's Disease.
Thursday, September 29, 2022: Quantifying Diversity and Inclusion in Clinical Research
Dr. Jonathan Jackson, PhD, Executive Director of the Community Access, Recruitment, and Engagement (CARE) Research Center at Massachusetts General Hospital, examines diversity in clinical research and proposes a novel framework for understanding and improving representation and generalizability in clinical research.
Gonzalez-Perez (9/22/22)
Thursday, September 22, 2022: Case Records of the MGH - An 80-year-old man with foot drop
Meridale Baggett, MD, Paloma Gonzalez-Perez, MD, PhD, Reza Seyedsadjadi, MD, Johnny-Joshua Okonkwo, MD, Karen Buch, MD
Thursday, September 8, 2022: Neurology Grand Rounds: Angelman Syndrome and 15q Duplication Syndrome
Dr. Ronald Thibert, Director of the MGH Dup15 Clinic and the Angelman Syndrome Clinic and Co-Director of the Pitt Hopkins Syndrome Clinic discusses the growing role of rare disease clinics and gene therapy development to improve care and outcomes in patients with Angelman Syndrome and 15q Duplication Syndrome.
Levy CPC (6/23/22)
Thursday, June 23, 2022: Case Study - A 30 year old woman with monocular vision loss
Meridale Baggett, MD, Michael Levy, MD, PhD
Thursday, June 9, 2022: ALS in 2022: New Insights in Biology and Treatments
In the Richard Tyler Memorial Lecture, Mass General Chief of Neurology Merit Cudkowicz, MD, MSc discusses current treatment and diagnostic approaches in ALS, new clinicaltrial designs such as the HEALEY ALS Platform Trial and new treatment approaches being developed for people with ALS.
Thursday, April 28, 2022: Women & Stroke: The Importance of Age and Sex
For the 2022 C. Miller Fisher Memorial Lecture, Louise D. McCullough, MD, PhD, the Chief of Neurology at Memorial Hermann Hospital, discusses sex differences in stroke and how they increase mortality and morbidity.
Thursday, April 12, 2022: NEJM Clinicopathological Conference, A 68-Year-Old Man with Recurrent Strokes
MGH neurologist Aneesh B. Singhal, M.D., M.B.,B.S. reviews the case of a 68-year-old man with worsening confusion. He is joined in discussion by Scott B. Silverman, M.D. from MGH Neurology, Javier M. Romero, M.D. from MGH Radiology, and Melanie Lang-Orsini from MGH Pathology. The proceedings of this discussion appear in the February 23, 2023 edition of the New England Journal of Medicine as Case 6-2023.
March 17, 2022: Innovating Care Models in Neuro-Oncology
Rochester University Neurologist and Oncologist Nimish Mohile, MD, MS, FAAN discusses the challenges of cancer care delivery for patients with primary brain tumors, ways to use design thinking approaches in modernizing clinical care and strategies to support innovation in academic neurology.
March 10, 2022: Neuro Aesthetics
Brigham & Women’s Neurologist Shahram Khoshbin, MD discusses the neurological basis of visual arts appreciation, ways in which physicians can enhance their clinical observational skills through visual arts principles, and the relationship between the arts and certain neurological disorders.
January 27, 2022: Infection as a Trigger for Arterial Ischemic Stroke: Lessons from Childhood Stroke Research
UCSF Professor Heather Fullerton, MD discusses mechanisms by which infection can contribute to the pathogenesis of arterial ischemic stroke. Dr. Fullerton is the Founder and President of the International Pediatric Stroke Organization (IPSO), a nonprofit organization that aims to improve the prevention, care and lifelong outcomes of children with cerebrovascular disease worldwide.
December 9, 2021: Precision Medicine & Drug Discovery
David Goldstein, PhD, the CEO and Co-Founder of Actio Biosciences, provides an introduction to diagnostic sequencing, its role in clinical practices, and assessment of its impact on drug development.
November 18, 2021: Autism for the Neurologist
University of Texas at Austin Neurologist Audrey Brumback, MD, PhD discusses subtle presentations of the core symptoms of autism, masking and camouflaging behaviors, and brain circuits being studied for their potential involvement in the condition.
October 21, 2021: Clinicopathological Conference: A 65-year-old Woman with a History of Childhood Measles Encephalitis
Christopher Stephen, MB ChB reviews the case of a 65-year-old woman with a history of childhood measles encephalitis now presenting with rapidly progressive right arm weakness and falls. He is joined by panelists Case Western Reserve Professor Brian Appelby, MD, Mass General Resident Marina Avetisyan, MD, PhD, Mass General Radiologist Pamela Shaefer, MD, and Mass General Neuropathologist Derek Oakley, MD, PhD.
September 2, 2021: Optogenetic and therapeutic approaches to slowing Alzheimer’s disease
Ksenia Kastanenka, PhD discusses the role of sleep rhythms in Alzheimer’s disease progression, how these rhythms can be manipulated in mouse models of the disease and the way that the new drug Aducanumab affects calcium levels in neurons.
July 22, 2021: Balancing Risk and Benefit: Protecting the Brain from Seizures and Overtreatment during Critical Illness
Sahar Zafar, MD discusses ways that physicians can protect the brain from seizures and the danger of overtreatment during care for critical illness. Dr. Zafar is the Associate Medical Director of the MGH Neuroscience Intensive Care Unit and Director of the Mass General Brigham Neurocritical Care Fellowship at Harvard Medical School.
July 15, 2021: Challenges in Medical Education
Tracey Cho, MD leads a discussion on the best ways to develop and share knowledge in clerkship and residency programs. Dr. Cho is the Vice Chair for Education at the University of Iowa Carver College of Medicine and a graduate of the Mass General Brigham Neurology Residency.
July 8, 2021: Clinicopathological Conference: A 67-year-old Man with Progressive Motor Neuron Disease
Meridale Baggett, MD reviews the case of a 67-year-old man with progressive motor neuron disease, obstructive sleep apnea, somnolence, and odd behaviors during sleep. She is joined by Mass General Neurologists Suma Babu, MD, MPH, MBBS; Jenny Linnoila, MD, PhD; Haatem Reda, MD and Aleksandar Videnovic, MD, MSc, as well as Neuroradiology Fellow Brian Zhao, MD.
Watch recording
May 20, 2021: C. Miller Fisher Visiting Professor Lecture: Out of Africa: Emerging Stroke Situation, Science, Scientists, and Strategies
Bruce Ovbiagele, MD, MSc, MAS, MBA presents information on the public promise and challenge of delivering and expanding stroke care throughout Africa. Dr. Ovbiagele is a professor of Neurology and an Associate Dean at the University of California, San Francisco.
May 13, 2021: Seizures after Acute Brain Injury
Kevin Staley, MD, the Chief of the Section of Child Neurology at Mass General and principal investigator of the Pediatric Epilepsy Research Lab, discusses brain injury and seizures.
April 8, 2021: Clinicopathological Conference: A 55-year-old Man with Hearing Loss & Eye Redness
Meridale Baggett, MD reviews the case of a 55-year-old man with bilateral hearing loss & eye redness. She is joined by UCSD Professor of Otolaryngology & Neurological Surgery Jeffrey Harris, MD, PhD, FACS; Mass General Infectious Disease Physician Andrea Ciaranello, MD; and Mass General Residents Mia Bothwell, MD, PhD and Elisabeth Tabb, MD.
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March 25, 2021: Tyler Memorial Neurology Grand Rounds: Immune Mechanisms in Neurologic Diseases
Howard Weiner, MD discusses how the innate and adaptive immune systems contribute to neurologic disease and how they can be used to treat it. Dr. Weiner is the Robert L. Kroc Professor of Neurology at Harvard Medical School, the Director and Founder of the Brigham MS Center and the Co-Director of the Ann Romney Center for Neurologic Diseases at Brigham and Women's Hospital.
March 18, 2021: Three Short Stories in Neuroimmunology
Michael Levy, MD, PhD, director of the Mass General Neuroimmunology Clinic & Research Lab, discusses neuromyelitis optica spectrum disorder (NMOSD) and MOG antibody disease (MOGAD), their immunological differences and treatment options.
February 18, 2021: Modeling the Complexity of Migraine: Challenges and Future Directions
Mass General Neurologist Andrea Harriott, MD, PhD, discusses the utility of in-vitro models of migraine in the preclinical setting and of behavioral models of migraine with aura in the preclinical setting.
February 11, 2021: Computable Neurologic Phenotypes in Pediatric Critical Care
University of Washington Professor Mark Wainwright, MD, PhD, FAAN discusses pediatric neurocritical care, including neuromonitoring methods and the potential of electronic health records and streaming physiologic data to identify risks of neurologic injury in the ICU.
January 28, 2021: Changing the Paradigm for ALS Clinical Trials
Sabrina Paganoni, MD, PhD presents the Krivickas Memorial Grand Rounds Lecture, focusing on the success of new clinical trials for ALS in the past year, including the CENTAUR trial and the HEALEY ALS Platform Trial.
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January 21, 2021: Clinicopathological Conference: A 64-year-old Woman with Headaches, Memory Loss, and Cognitive Impairment
Meridale Baggett, MD reviews the case of a 64-year-old woman with 6 weeks of headaches, memory loss, and cognitive impairment. She is joined by Brigham & Women’s Neurologist Shamik Bhattacharyya, MD, MS; Mass General Neuropathology Fellow Samantha Champion, MD; Mass General Neurologist Bart Chwalisz, MD and Mass General Neuroradiologist Ramon Gonzalez, MD, PhD.
December 10, 2020: The Role of Pandemics in the Evolution and Destruction of the Human Brain
Avindra Nath, MD, Chief of the Section of Infections of the Nervous System at NIH, covers neurological complications associated with recent and remote pandemics, the way that pandemics have shaped human evolution and brain development, and how pathogens incorporated in the human genome from remote pandemics can influence the pathophysiology of neurodegenerative diseases.
November 19, 2020: Neuro-Vascular Interactions in the Brain
Chenghua Gu, DVM, PhD, a Professor of Neurobiology at Harvard Medical School, explains molecular mechanisms underlying the blood-brain barrier and neurovascular coupling.
September 17, 2020: Case Record Review with Meridale Baggett, MD
Meridale Baggett, MD, leads a case discussion about a 65-year-old man with eye pain and decreased vision. Dr. Baggett is the Associate Editor, New England Journal of Medicine Case Records of the Massachusetts General Hospital.
May 14, 2020: Case Study: A 60-year-old woman with COVID-19 and altered mental status
Moderator: Meridale Baggett, MD, Associate Editor, New England Journal of Medicine Case Records of the Massachusetts General Hospital
Panel: Aneesh Singhal, MD, Bart Chwalisz, MD, Shibani Mukerji, MD, PhD and Ramon Gonzalez, MD
April 30, 2020: Neurology & COVID-19 Research Update
Presenters Jonathan Rosand, MD, Mark Albers, MD and Eric Klawiter, MD, MSc share new information about COVID-19 clinical trials and ongoing research.
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April 23, 2020: COVID-19 & Neurology: A Panel Discussion
Presenters Bart Chwalisz, MD, M. Brandon Westover, MD, PhD, Paloma Gonzalez-Perez, MD, PhD and Shibani Mukerji, MD, PhD discuss the neurological impacts of COVID-19.
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Accreditation
Mass General Brigham is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
Mass General Brigham designates this live activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
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