Myasthenia Gravis Clinic

Our Approach to Diagnosing and Treating MG

We provide compassionate care for patients with autoimmune myasthenia gravis (MG), congenital myasthenic syndromes and Lambert-Eaton Myasthenic Syndrome (LEMS). Our goal is to develop a highly personalized approach to treatment of your myasthenia, which brings the most up to date therapies and research opportunities to our patients.  We have been recognized as an “MG Partners in Care” Clinic by the Myasthenia Gravis Foundation of America. 

Our Services and Facilities

• Initial Consultation or Second Opinion
• Follow-up Care
• Electrodiagnostic testing, Electromyography, Repetitive Nerve Stimulation Studies, Single Fiber EMG - Our facility includes an onsite Electromyography (EMG) Laboratory where we perform repetitive nerve stimulation and/or single fiber EMG studies if needed to confirm the diagnosis of MG

• Clinical Research and Clinical Trials

• Virtual Visits
• Online Second Opinions

• Optometry and Neuro-ophthalmology

• Infusion Center: If infusion therapies are indicated, Mass General's Medical Infusion Center in Boston or Waltham is experienced with treatment of patients with MG.  Our staff also coordinates with local home infusion services. Therapeutic Plasma Exchange is performed by the expert staff in the Blood Transfusion Service at Mass General in Boston. 
• Special interests, including care of MG during pregnancy or immunotherapy cancer treatment

The MG clinic is located within the neuromuscular clinic on the main MGH campus in Boston, at 165 Cambridge Street in the Charles River Plaza.  We provide both morning and afternoon appointments to fit your schedule.

What to Expect at Your Visit

During your clinic visit, our team will review your symptoms and perform a neurologic examination. We will review your medications, allergies, and personal and family medical histories.  We will ask detailed questions about your history of myasthenia gravis including your diagnosis (antibody status, prior EMG studies) and whether you have had a thymectomy or thymoma. We will also ask details about what medications you have taken for MG. Through discussion and your completion of myasthenia-specific scales, we will explore the impact of your MG symptoms on your daily activities and quality of life. Finally, we will talk to you about ongoing research studies and new developments in the field.

Research and Clinical Trials

The Mass General MG clinic is at the forefront of research in MG. We provide access to industry- and NIH-supported clinical trials. Our central goal is to improve the diagnosis and treatment of myasthenia gravis. We are currently a site in the NIH funded Rare Disease Registry, MGNET.  Dr. Amanda Guidon’s research in MG has been funded by the Myasthenia Gravis Foundation of America and MGNET.