About Sydney Cash, MD, PhD

Sydney S. Cash, MD, PhD, received his MD and PhD degrees from Columbia University College of Physicians and Surgeons, completed his Neurology residency and was a Chief Resident at MGH and BWH. Dr. Cash is on the Neurology staff at MGH, and is an Assistant Professor in Neurology at Harvard Medical School. Dr. Cash is a specialist in epilepsy with research expertise in cortical microphysiology, including research with the investigating the mechanisms of diseases such as epilepsy and ways of interfacing with the brain for improving the lives of people with seizures, paralysis and other neurological difficulties.

Departments, Centers, & Programs:

Clinical Interests:

Treats:

Locations

Mass General Neurology
55 Fruit St.
Boston, MA 02114
Phone: 855-644-6387

Medical Education

  • MD, Columbia University College of Physicians & Surgeons
  • Residency, Brigham and Women's Hospital

American Board Certifications

  • Neurology, American Board of Psychiatry and Neurology

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Research

The focus of Dr. Cash's lab is on trying to understand how the brain works under both normal and pathological conditions with an ultimate goal of developing techniques for diagnosing and treating some of the most devastating diseases. We are particularly focused on using approaches which extract information at multiple scales and then combine them into a more complete and meaningful understanding of brain physiology. We feel this multi-scalar, multi-modal approach is particularly powerful for understanding the human brain because of its complexity and architecture which is, by nature, multi-scalar.

We employ non-invasive measures of brain activity (MEG, EEG, fMRI) and structure (MRI) to get a holistic view of the brain.  We also use very specialized methods of recording directly from either human or rodent cortex including techniques to record the activity of single human neurons while patients are awake (microelectrode recordings) and optogenetic methods to control individual neurons.  Our projects are focused on understanding four core, but overlapping, areas:

1. Normal cognition

2. The physiology and importance of sleep and dreaming

3. The basic physiology of cortical and subcortical oscillations

4. Controlling seizures

Long-range goals include the development of new methods for identifying seizure areas, predicting seizures and then stopping them. We are also using these techniques to move toward new ways of interacting directly with the human nervous system for diagnosis and repair or replacement (neuroprosthetics and brain-computer interfaces) of damaged nervous system tissue.

Cortical Physiology Laboratory at Mass General.

Publications

Reviews: Comments and Ratings

4.9out of 5(39 Ratings, 10 Comments)

October 2024

Dr. Cash is very knowledgeable and kind


October 2024

I think Mr. Cash is awesome. He's been with me through my whole trial and error system. I would definitely recommend him to anybody. I've been with him for over 10 years and I wouldn't have it any other way.


October 2024

Dr. Cash was excellent, even though this was the first time we met, he knew my information as if we'd been working together for months. He was very intelligent and insightful on my condition, possibilities and courses of action moving forward. He was extremely respectful and listened to everything my wife and I both had to say. If that wasn't ... Read More


October 2024

Have had this care provider for many years and always enjoy our visit whether on line or in person. The knowledge shown is always helpful to me.


September 2024

Dr. Cash is thorough, efficient, and down to earth and compassionate for the client care. That's why I continue to see him and will continue to do so while he helps resolve and sustain my health.


September 2024

Dr Cash goes above and beyond and thankfully thinks outside the box when it comes to all of my medical


May 2024

Dr. Sydney Cash is very knowledgeable and very professional and we enjoy working with him. And thank you to Mass General Hospital. Thank you.


May 2024

Dr. Cash is one of the best doctors we've ever worked with. He listens, he knows [redacted] so well, he explains everything on an easy level for us to understand. He gives us all of his time and we couldn't ask for more.


April 2024

Dr Cash is amazing! We justice him!


March 2024

I felt well cared for by this provider. Thank you!

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