About Merit Cudkowicz, MD, MSC

Departments, Centers, & Programs:

Clinical Interests:

Treats:

Languages:

Locations

Mass General Neurology
55 Fruit St.
Boston, MA 02114
Phone: 855-644-6387

Sean M. Healey and AMG Center for ALS
55 Fruit Street
8th Floor
Boston, MA 02114
Phone: 617-724-3914

Mass General Neurology: Neurological Clinical Research Institute
165 Cambridge St.
6th Floor
Boston, MA 02114
Phone: 617-726-5732

Medical Education

  • MD, Harvard Medical School
  • Residency, Massachusetts General Hospital
  • Fellowship, Massachusetts General Hospital

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Research

My research activities are dedicated to the study and treatment of patients with Amyotrophic Lateral Sclerosis (ALS) and other neurological disorders. As Director of the MGH Neurological Clinical Research Institute and the Principal Investigator for the NINDS supported NeuroNEXT Clinical Coordinating center (www.neuronext.org), I  design clinical trials to evaluate the safety and effectiveness of therapies that have shown promise in preclinical studies. In ALS, I co-founded an international consortium to test novel therapies in ALS, the Northeast ALS (NEALS) consortium. The NEALS consortium consists of over 128 clinical sites in the United States and Canada dedicated to performing joint academic led clinical trials in ALS.. We are leading several new trials in ALS. There is a critical need in neurology for highly trained clinical investigators who work collaboratively with basic scientists to develop new therapeutic strategies.

In 2018 we launched the Sean M. Healey & AMG Center for ALS at Mass General. This new Center is dedicated to accelerating therapy development and access to treatments for people with ALS. We are launching the first Platform Trial initiative in ALS where several treatments will be tested in one platform approach. This groundbreaking initiative will cut in half the time to develop treatments, increase by 67% ability of people to receive active treatment and cut costs of drug development by 33%. This approach, already successful in oncology, will revolutionize how treatments are developed in ALS. The Healey Center bring collaborators from around the world to work together to find treatments for people with ALS.

Publications