The last decade has seen unprecedented advances in our understanding of the biology of the disease, an exponential increase in novel targets and innovative approaches to developing therapies. The annual Sean M. Healey International Prize for Innovation in ALS is a global prize celebrating excellence in research for a team of investigators who catalyse exceptional discoveries leading to a transformative advance in therapy development in ALS. 

Sean M. Healey, executive chairman of Affiliated Managers Group, Inc. (AMG) joined AMG when it was a start-up in 1995 and together with his founding colleagues built the firm into one of the largest global asset management companies with over $830 billion under management – AMG is NYSE-listed and a component of the S&P 500. Prior to AMG, Sean began his career as an investment banker in the Mergers and Acquisitions Department at Goldman Sachs.

Mr. Healey was diagnosed with ALS in May 2018. Following his diagnosis, he took a step back from his long-time role of Chairman and CEO at AMG to aggressively pursue treatment at the guidance of his doctor, Merit Cudkowicz, MD, MSc, Chief of Neurology at Mass General. Together, with his company and friends, he established the Sean M. Healey & AMG Center for ALS at Mass General.

2025 Nomination Portal

Prize Criteria

Team of investigators who made a significant advance in the ALS field impacting the development of novel therapies for ALS, including, but not limited to the following:

  • A technology to identify novel targets for drug development
  • A technology to advance therapy development for ALS
  • Tools or targets to stratify the ALS population and improve clinical trial design
  • A global, multiple disciplinary collaboration that leads to new insights into the biology of the disease and translates into novel approaches for therapy development
  • A novel outcome measure to improve efficiency in clinical trials in patients with ALS

Timeline for Submission

  • Nomination Due Date: Wednesday, July 9th, at 5 pm EDT
  • Presentation of Award: International Symposium on ALS/MND December 5-7, 2025
  • Award: $50,000 USD and travel reimbursement up to $2,500 USD to attend International Symposium on ALS/MND

   Submit completed nomination form via portal 

If you need assistance completing the nomination form, please contact healeyamgcenterforals@mgh.harvard.edu