Center for Genomic Medicine

The goal of the Massachusetts General Hospital Center for Genomic Medicine (CGM) is the promulgation of the Genomic Medicine Cycle.

The CGM is leading an effort to complete the genomic medicine cycle—from genetic discoveries to mechanism to the clinic—by assessing where genomic medicine will have the greatest impact on human health, and by driving efforts to implement genomic medicine in those areas, at Mass General and beyond.

The cycle is a paradigm for disease research that begins by comparing human phenotypes and genetic variation to identify genes of importance in human disease, then moves on to characterizing the mechanisms by which the underlying DNA differences lead to disease, and is completed when the knowledge gained delivers benefit back to patients in the forms of improved diagnosis, disease management and treatments.

Faculty

Christopher D. Anderson, MD, MMSc
Assistant Professor of Neurology, Harvard Medical School
Associate Director, Acute Stroke Service, Massachusetts General Hospital

Susan L. Cotman, PhD
Assistant Professor of Neurology, Harvard Medical School
Assistant in Neuroscience, CGM & Department of Neurology, Massachusetts General Hospital

William Crowley, MD
Daniel K. Podolsky Professor of Medicine, Harvard Medical School
Chief of the Reproductive Endocrine Unit, Massachusetts General Hospital
Adjunct Faculty, Broad Institute, Medical Population Genetics Program
Director/Principal Investigator, NIH-funded Harvard-wide Reproductive Endocrine Sciences Translational Research Center

Mark Daly, PhD
Chief, Analytic and Translational Genetics Unit, Massachusetts General Hospital
Associate Professor of Medicine, Harvard Medical School
Senior Associate Member, Broad Institute

Alysa Doyle, PhD
Assistant Professor of Psychiatry, Harvard Medical School
Director of Research, Learning and Emotional Assessment Program, Massachusetts General Hospital
Associate Researcher, Stanley Center for Psychiatric Research

Erin Dunn, ScD, MPH
Assistant Professor of Psychiatry, Harvard Medical School

Florian Eichler, MD
Director, Center for Rare Neurological Diseases, Massachusetts General Hospital
Associate Professor of Neurology, Harvard Medical School

Jose C. Florez, MD, PhD
Professor of Medicine, Harvard Medical School
Chief, Diabetes Unit, Massachusetts General Hospital
Institute Member, Broad Institute

Yulia Grishchuk, PhD
Instructor in Neurology, Massachusetts General Hospital
Assistant in Neuroscience, Harvard Medical School

James Gusella, PhD
Bullard Professor of Neurogenetics, Harvard Medical School
Director, Center for Neurofibromatosis and Allied Disorders, Harvard Medical School

Stephen J. Haggarty, PhD
Associate Professor of Neurology, Harvard Medical School

Rakesh Karmacharya, MD, PhD
Associate Professor of Psychiatry, Harvard Medical School

Sekar Kathiresan, MD
Professor of Medicine on Leave of Absence

Raymond J. Kelleher III, MD, PhD
Assistant Professor of Neurology, Harvard Medical School

Amit V. Khera, MD, MSc
Associate Director, Precision Medicine Unit, CGM, Massachusetts General Hospital
Associate Director, Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard
Instructor of Medicine, Harvard Medical School
Cardiologist, Corrigan Minehan Heart Center, Massachusetts General Hospital

W. Taylor Kimberly, MD, PhD
Associate Professor of Neurology, Harvard Medical School
Associate Director, Neuroscience ICU, Massachusetts General Hospital
Associate Chief, Division of Neurocritical Care & Emergency Neurology, Massachusetts General Hospital

Ben Kleinstiver, PhD
Assistant Investigator, Pathology, Massachusetts General Hospital
Assistant Professor of Pathology, Harvard Medical School

Jong-Min Lee, PhD
Assistant Professor of Neurology, Harvard Medical School

Phil Hyoun Lee, PhD
Assistant Professor of Psychiatry, Harvard Medical School

Daniel MacArthur, PhD
Assistant Professor of Medicine, Harvard Medical School
Co-Director of Medical and Population Genetics at, Broad Institute

Marcy E. MacDonald, PhD
Professor of Neurology, Harvard Medical School
Faculty, Basic Biological Sciences, Harvard Medical School
Non-clinical Staff, Massachusetts General Hospital
Associate Member, Broad Institute

Vamsi K. Mootha, MD
Investigator, Howard Hughes Medical Institute (HHMI)
Professor of Systems Biology and Medicine, Harvard Medical School
Institute Member, Broad Institute

Ricardo Mouro Pinto, PhD
Instructor in Neurology, Harvard Medical School

Patricia Musolino, MD, PhD
Assistant Professor of Neurology, Harvard Medical School
Co-Director of the Pediatric Stroke & Cerebrovascular Service, Massachusetts General Hospital

Benjamin Neale, PhD
Associate Professor of Medicine, Harvard Medical School
ATGU, Massachusetts General Hospital
Director of Population Genetics, Stanley Center for Psychiatric Research, Broad Institute

Christopher Newton-Cheh, MD, MPH
Assistant Professor of Medicine, Harvard Medical School
Faculty, Cardiovascular Research Center, Massachusetts General Hospital
Associate Member, Broad Institute

Aarno Palotie, MD, PhD
Lecturer, Harvard Medical School

Roy H. Perlis, MD, MSc
Professor of Psychiatry, Harvard Medical School
Director, Center for Experimental Drugs and Diagnostics, Massachusetts General Hospital

Vijaya Ramesh, PhD
Professor of Neurology, Harvard Medical School

Heidi L. Rehm, PhD, FASMG
Chief Genomics Officer, Department of Medicine, Massachusetts General Hospital
Medical Director, Broad Institute Clinical Research Sequencing Platform
Professor of Pathology, Harvard Medical School

Jonathan Rosand, MD, MSc
Professor of Neurology, Harvard Medical School
J.P. Kistler Neurologist, Massachusetts General Hospital
Chief, Neurocritical Care & Emergency Neurology, Massachusetts General Hospital
Co-Director, Institute for Brain Health, Massachusetts General Hospital
Associate Member, Broad Institute

Richa Saxena, PhD
Associate Professor of Anaesthesia, Harvard Medical School
Phyllis and Jerome Lyle Rappaport MGH Research Scholar
Associate Member, Medical and Population Genetics, Broad Institute

Jeremiah Scharf, MD, PhD
Assistant Professor of Neurology, Harvard Medical School
Co-Director, Tourette Association of America Center of Excellence, Massachusetts General Hospital
Co-Chair, Tourette Syndrome Association International Consortium for Genetics

Ihn Sik Seong, PhD
Assistant Professor of Neurology, Harvard Medical School

Brian Skotko, MD, MPP
Assistant Professor of Pediatrics, Harvard Medical School
Co-Director, Down Syndrome Program, Massachusetts General Hospital

Susan A. Slaugenhaupt, PhD
Scientific Director, Mass General Research Institute
Interim Director, Center for Genomic Medicine, Massachusetts General Hospital
Professor of Neurology (Genetics), Harvard Medical School

Jordan W. Smoller, MD, ScD
Professor of Psychiatry, Harvard Medical School
Director, Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital

Alexander Soukas, MD, PhD
Assistant Professor of Medicine, Harvard Medical School

David Sweetser, MD, PhD
Assistant Professor of Pediatrics, Harvard Medical School
Chief of Medical Genetics and Metabolism, Massachusetts General Hospital
Co-Director Pitt Hopkins Syndrome Clinic, Massachusetts General Hospital
Mass General Site Director, Undiagnosed Diseases Network

Kathryn J. Swoboda, MD
The Katherine B. Sims M.D. Endowed Chair in Neurogenetics
Director of the Neurogenetics Program at Massachusetts General Hospital/Harvard Medical School

Michael Talkowski, PhD
Associate Professor of Neurology, Harvard Medical School

James Walker, PhD
Assistant Professor of Neurology, Harvard Medical School
Assistant in Genetics, Massachusetts General Hospital
Associate Member, Broad Institute

Vanessa Wheeler, PhD
Associate Professor of Neurology, Harvard Medical School