Researchers find immune cell “hubs” in certain tumors

Immune cells in some human colorectal tumors congregate in clusters, scientists report in Cell. The researchers, from MGH, the Broad Institute of MIT and Harvard, MIT, the Evergrande Center for Immunologic Diseases at Brigham and Women’s Hospital and Harvard Medical School, and Dana-Farber Cancer Institute say that these “hubs” might be likelier to respond to immunotherapies.

Nir Hacohen, PhD, who is the David P. Ryan, MD, Endowed Chair in Cancer Research at MGH and director of the Center for Cancer Immunology, is co-senior author of the study.

Read the full story from the Broad Institute here.