Research Spotlight: Lower Hydroxychloroquine Dosing is Less Effective in Preventing Lupus Flares
Hydroxychloroquine dosing under 5 mg/kg/day is less effective in preventing lupus flares than higher dosing.
About Hyon Choi, MD
Dr. Hyon Choi received his rheumatology fellowship training at Massachusetts General Hospital and Harvard Medical School, and his master's and doctorate degrees in epidemiology from Harvard University. Dr. Choi has been a leading clinical rheumatologist and investigator with a primary focus on gout, rheumatoid arthritis, and psoriatic arthritis throughout his academic career, as reflected by his funding (National Institutes of Health [NIH] and industry), publications (over 200, including >60 gout-related peer-reviewed papers including those published in NEJM, JAMA, Lancet, Nat Genet, Ann Int Med, BMJ, Arch Int Med, Am J Med, Ann Rheum Dis, A&R), and reviewer activities for top journals and the NIH. The significance of Dr. Choi?s contributions has been widely accepted by the field, and his findings have been referenced by many articles as well as by the recent guidelines from the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR, 2012). His clinical and epidemiologic research has provided state-of-the-art evidence to inform the gout field, which is needed to move its guidelines from expert-consensus to an evidence-based approach.
Clinical Interests:
- ANCA-associated vasculitis
- Giant cell arteritis
- Gout and pseudogout
- Lupus
- Psoriatic arthritis
- Rheumatoid arthritis
- Sjogren's syndrome
Treats:
- Adult
Languages:
- Korean
Locations
Mass General Rheumatology
55 Fruit St.
Yawkey Center for Outpatient Care
Suite 4B
Boston, MA 02114
Phone: 617-726-7938
Medical Education
- MD, Yonsei University College of Medicine
- Residency, MetroWest Medical Center***
- Fellowship, Barnes Jewish Hospital
- Fellowship, Massachusetts General Hospital
American Board Certifications
- Rheumatology, American Board of Internal Medicine
Accepted Insurance Plans
- Aetna
- Beech Street
- Blue Cross Blue Shield
- Blue Cross Blue Shield Medicare
- Cigna
- Commonwealth Care Alliance
- Coventry
- Fallon Health
- Harvard Pilgrim Health Care
- Humana
- Maine Community Health Options
- Mass General Brigham Health Plan
- MassHealth
- Medicaid ME
- Medicaid RI
- Medicaid VT
- Medicare
- Medicare ACO
- Multiplan
- Senior Whole Health
- TriCare
- Tufts Health Plan
- United Health Care
- Wellpoint
- WellSense
Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.
Research
Dr. Choi has been a leading physician investigator with primary focus on gout and other inflammatory arthritic conditions throughout his academic career. His research has been funded by the NIH, Rheumatology Research Foundation, and industry, resulting in >200 publications (including those published in NEJM, JAMA, Lancet, Nat Genet, Ann Int Med, BMJ, Ann Rheum Dis, A&R). His research findings have been referenced by many subsequent publications by others, including the recent guidelines from the European League Against Rheumatism and the American College of Rheumatology (2012). As follows, Dr. Choi's novel discoveries have provided new avenues for simple, safe, and cost-effective prevention strategies for hyperuricemia and gout, including the: 1) protective impact of dairy products; 2) hazardous impacts of sugar-sweetened soda and fructose; 3) protective impact of vitamin C; 4) protective impact of coffee; 5) protective impacts of losartan and calcium channel blockers; and 6) hazardous impacts of other classes of anti-hypertensives. Dr. Choi's research has extended to the genetics of gout and gene-environment interactions, which has led to several international collaborations and key discoveries in the field (Nat Genet 2013 and Nature2014). He has also led a multidisciplinary team for several key investigations, which have demonstrated the remarkable potential of Dual Energy Computed Tomography as an innovative tool for visualizing uric acid crystal deposits in articular and extra-articular tissue. Beyond gout research, Dr. Choi has applied innovative methodologic approaches to various rheumatic disease contexts and carried out several groundbreaking studies ,including a state-of-the-art causal analysis on the survival benefit of methotrexate (Lancet 2004).
I've seen Dr. Choi for quite a long time. I saw other providers for a few years when he was out on the West Coast in Canada, actually. Dr. Choi is an excellent physician, superb physician. And I've had an excellent rapport with him from when I was diagnosed in 2000 until now. So 25 years, he's been my doctor except for a period when he was in ... Read More
He is a great doctor.
Dr. Choi carefully reviewed the current status of my left foot pain, apparently caused by chronic gout and/or osteoarthritis. He ordered a serum urate level blood test and followed up within hours of receiving the test results by recommending an increase in my allopurinol dose and ordering a repeat serum urate blood test in two weeks. I very much ... Read More
Dr. Choi is a pleasant skilled professional. I am fortunate to have him as my Rheumatologist.
Very knowledgeable and exceptional.
Very knowledgeable and caring, takes time to listen
I appreciate the professionalism and friendliness of everyone I dealt with in the rheumatology department.
Very responsive and informative.
Dr. Choi seems thoughtful when considering my medications and the best treatment options for me,
Dr. Choi is kind, thoughtful, and of course, very intelligent and experienced in the field. It was great to see him after several years of absence due to COVID and things that followed. He even remembered important details about my husband. He knows me and he cares about me a lot. It was great to be connected with him again. Thank you.