About Shizuo Mukai, MD

Dr. Mukai is a clinician scientist with clinical expertise in the surgical and medical management of vitreoretinal diseases, including complex retinal detachments, pediatric retina, intraocular tumors of the posterior segment (especially retinoblastoma), genetic retinal diseases, and retinal imaging. His research interests include molecular biology of retinal diseases (especially retinoblastoma) and proliferative vitreoretinopathy, new treatment approaches to retinoblastoma, smartphone-based retinal imaging and computerized image analysis, phenotype-genotype correlations in genetic retinal conditions, and retinal stem cells.

Departments, Centers, & Programs:

Clinical Interests:

Treats:

Languages:

Locations

Mass Eye and Ear
243 Charles St.
Boston, MA 02114
Phone: 617-523-7900

Medical Education

  • MD, Brown University
  • Residency, Massachusetts Eye and Ear
  • Fellowship, Massachusetts Eye and Ear

American Board Certifications

  • Ophthalmology, American Board of Ophthalmology

Research

Dr. Mukai is a clinician scientist with clinical expertise in the surgical and medical management of vitreoretinal diseases, including complex retinal detachments, pediatric retina, intraocular tumors of the posterior segment (especially retinoblastoma), genetic retinal diseases, and retinal imaging. His research interests include molecular biology of retinal diseases (especially retinoblastoma) and proliferative vitreoretinopathy, new treatment approaches to retinoblastoma, smartphone-based retinal imaging and computerized image analysis, phenotype-genotype correlations in genetic retinal conditions, and retinal stem cells.

Publications

  • 1. Wu W, Zhou G, Han H, Huang X, Jiang H, Mukai S, Kazlauskas A, Cui J, Matsubara JA, Vanhaesebroeck B, Xia X, Wang J, Lei H. PI3Kd as a Novel Therapeutic Target in Pathological Angiogenesis. Diabetes. 2020 Jan 08.

    2. Nguyen HV, Nagata T, Mukai S. Inexpensive and Open-Source Devices and Systems for Retinal Imaging. Int Ophthalmol Clin. 2020; 60(1):35-45.

    3. Golas L, Skondra D, Ittiara S, Bajic N, Jeng-Miller KW, Mukai S, Yonekawa Y, Blair MP. Efficacy of Retinal Lesion Screening in Von Hippel-Lindau Patients With Widefield Color Fundus Imaging Versus Widefield FA. Ophthalmic Surg Lasers Imaging Retina. 2019 Nov 01; 50(11):e260-e265. 

    4. Gupta MP, Dow E, Jeng-Miller KW, Mukai S, Orlin A, Xu K, Yonekawa Y, Chan RVP. SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN COATS DISEASE. Retina. 2019 Jun; 39(6):1177-1185.

    5. Lee Kim E, Weiner AJ, Ung C, Roh M, Wang J, Lee IJ, Huang NT, Stem M, Dahrouj M, Eliott D, Vavvas DG, Young LHY, Williams GA, Garretson BR, Kim IK, Hassan TS, Mukai S, Ruby AJ, Faia LJ, Capone A, Comander J, Kim LA, Wu DM, Drenser KA, Woodward MA, Wolfe JD, Yonekawa Y. Characterization of Epiretinal Proliferation in Full-Thickness Macular Holes and Effects on Surgical Outcomes. Ophthalmol Retina. 2019 Aug; 3(8):694-702.

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Reviews: Comments and Ratings

4.9out of 5(154 Ratings, 65 Comments)

January 2025

Extremely intelligent in his field


January 2025

I always look forward to seeing Dr. Mukai, not just for his expertise in the retina field but also because he genuinely cares about all aspects of my health and life in general. He is a true gentleman while also being an expert in the retina field!


January 2025

I have been seeing Dr. Mukai for over 10 years. He's very respectful, polite, and probably one of the best doctors I've ever had.


January 2025

I appreciate the continued professionalism and care I receive from Dr. Mukai and his team.


January 2025

Dr Mukai has been my retina specialist for 32 years, and he is the best! There are no other words to describe his care, professionalism, concerns, and kindness. He is extremely quick to book me in if there is an emergency, as there was 2 years ago, and, in addition to his exemplary care, he is always ready to explain what has happened and his ... Read More


January 2025

Dr. Mukai is wonderful. I have grown up with him, and hope he continues to work a long time.


January 2025

MEE is a great place! I am fortunate to have Dr Mukai and his team as my providers. They are excellent and I appreciate them. Thank you.


December 2024

I am absolutely sure that if I did not have a strong relationship with this provider and I hadn't had it for many years, I would not be seeing today.


December 2024

Dr. Mukai has always been kind and, I can't think of the word, tells me exactly what's going on. So I know in my condition what's going to happen next and he's always been a great doctor for me.


December 2024

Excellent I've had Dr. Mukai for years

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