Lysosomal Disorders

Diseases We Treat

We provide comprehensive care and therapy to children and adults for the following conditions:

• Fabry disease
• Gaucher disease
• Pompe disease
• Mucopolysaccharidoses (MPS) conditions
• Alpha-Mannosidosis

Additional conditions are addressed through the Department of Neurology Lysosomal Disorders Program.

What to Expect at Your First Visit

If you have a known diagnosis: You will meet with a physician who specializes in lysosomal disorders. They will review your medical records, take a detailed medical history, and work with you to create a treatment plan. Expect the visit to take 60 to 80 minutes. Lab work and other orders and referrals will be recommended.

If you suspect a lysosomal disorder: You will meet with a genetic counselor who specializes in lysosomal disorders. They will review your medical records, take a detailed medical and family history, and recommend and coordinate follow up testing. Expect the visit to take about 60 minutes. In most cases, the visit can be virtual or in person.

If you would like to learn more about our clinic or schedule an appointment please call 617-726-3880.

Patient Resources

View the full collection of patient resources from the Lysosomal Disorders Clinic at MGfC.

For Referring Physicians

To refer a new patient to our service please fax a referral and relevant medical records to our clinic at 617-726-1566.

Our Team

Lysosomal Disorders Care Team

• Amel Karaa, MD

  • Assistant Professer Harvard Medical School
  • Director, Mitochondrial Disease Program
  • Director, Lysosomal Disorders Program
• Tamara Gesso

  • Clinic Coordinator
• Lauren O'Grady, MS, CGC

  • Genetic Counselor

Cardiologists

• Michael Fifer, MD

  • Co-director, Hypertrophic Cardiomyopathy Program
• Manuella Lahoud-Rahme, MD

  • Department of Pediatrics
• Steven Lubitz, MD,MPH

  • Cardiology
  • Department of Medicine
• Ana Rosales, MD

  • Assistant in Pediatrics
  • Assistant Professor of Pediatrics Harvard Medical School
  • Fellow of the American Academy of Pediatrics
• Albree Tower-Rader, MD

  • Cardiology
  • Department of Medicine
  • Radiology

Nephrologist

• Andrew Lundquist, MD,PhD

  • Assistant Clinical Director, Nephrology - Department of Medicine

Neurologists

• Natalia Rost, MD

  • Chief, Stroke Division, Department of Neurology
  • Associate Director, MGH Comprehensive Stroke Center
  • Professor, Harvard Medical School
• Amanda Nagy, MD

  • Clinical Fellow in Neurology

Gastroenterologists

• Brad Kuo, MD

  • Gastroenterology
  • Department of Medicine
• Claire Zar-Kessler, MD

  • Medical Director, Pediatric Neurogastroenterology Program
  • Instructor, Harvard Medical School

Hematologists

• David Kuter, MD, Dphil

  • Hematology Program Director, Center for Hematology
• Annemarie Fogerty, MD

Orthopaedist

• Brian Grottkau, MD

  • Chief, Children's Orthopaedics
  • Pediatric Orthopaedic Surgeon
  • Assistant Professor of Orthopaedic Surgery, Harvard Medical School

Otolaryngologist/ENT

• Christopher Hartnick, MD

  • Massachusetts Eye and Ear Director, Division of Pediatric Otolaryngology
  • Director, Pediatric Airway, Voice, and Swallowing Center
  • Harvard Medical School Professor of Otolaryngology Head and Neck Surgery

Pulmonologist

• Bernard Kinane, MD

  • Chief, Pediatric Pulmonary Unit
  • Associate Chief for Education
  • Director of Pediatric Sleep Program and Pediatric Cardiopulmonary Exercise Laboratory