Dr. Young has written extensively on the morphologic features of ovarian and testicular cancer, several of the studies representing the largest reported experience with certain unusual neoplasms. He has also written papers on benign lesions that mimic cancer. Dr. Young has co-authored an Atlas of Gynecological Pathology. He is also a co-author with the late Dr. Robert Scully of the 3rd Series Fascicle on Tumors of the ovary, and with others of two other works in the same series, on tumors of the testis, and tumors of the prostate gland and related structures. He is director of annual courses on surgical pathology and gynecological pathology.
Dr. Young has published over 300 peer reviewed articles in the literature and about 100 reviews and chapters in books. In collaboration with David Louis, MD, Pathologist in Chief at Mass General, he edited Keen Minds to Explore the Dark Continents of Disease: A History of the Pathology Services at the Massachusetts General Hospital. He is director of a number of courses in Pathology for practicing pathologists offered through Harvard Medical School and has lectured throughout the world. Dr. Young was recently honored at the 2015 The One Hundred celebration, which is an awareness and fundraising initiative that celebrates hope in the cancer community.
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Mass General Pathology
55 Fruit St.
Boston, MA 02114
Phone: 617-643-0800
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Dr. Young's research includes clinicopathological studies in gynecological and urological pathology. In gynecologic pathology, ovarian tumors in the categories of the sex cord-stromal tumors and metastatic neoplasms are of particular interest. Dr. Young has written papers on sex cord tumors that have helped define their morphologic spectrum and clinical behavior. He has also highlighted the propensity for mucinous tumors metastatic to the ovary to simulate primary mucinous cancers of the ovary, work that has been confirmed by other observers. Studies continue on the exploration of various aspects of the morphology of primary and metastatic ovarian neoplasms. In the area of uterine pathology, Dr. Young's special interests at this time include the morphology of unusual variants of endometrial cancer and of endometrial stromal tumors. Dr. Young has written extensively on both benign and malignant glandular lesions of the cervix and has defined several new entities whose recognition has very important clinical consequences with regard to therapy.
In urologic pathology, Dr. Young's major interests are in bladder and testicular tumor pathology. Dr. Young and fellow collaborators have highlighted deceptively benign patterns of bladder cancer that can cause them to be misinterpreted as benign lesions. In companion with that area of investigation he has explored the morphology of the converse problem, namely the misinterpretation of various benign lesions as cancer. In the area of testicular pathology work has included description of variant patterns of germ cell and sex cord stromal tumors.
For more information about research concepts, co-authors, and to see a timeline, visit Dr. Young's profile at the Harvard Clinical and Translational Science Center.
