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About the Unit

Psychiatric and neurodevelopmental disorders are common, costly and often disabling conditions that affect individuals throughout their lives. Disability associated with neuropsychiatric disorders exceeds that of other medical illnesses, and psychiatric disorders are also associated with premature mortality. Familial and genetic factors are the most-substantiated risk factors for a broad range of neuropsychiatric disorders.

The Psychiatric & Neurodevelopmental Genetics Unit (PNGU) at Massachusetts General Hospital is working to identify and characterize the genetic basis of these disorders and offer hope for improving treatment and prevention strategies.

Faculty Members

The Psychiatric & Neurodevelopmental Genetics Unit is made up of researchers focused on a wide range of psychiatric disorders.

Meet our faculty

Software

MEGHA: Massively Expedited Genome-wide Heritability Analysis

MEGHA is a MATLAB toolbox for fast and flexible high-dimensional heritability analysis using genome-wide single nucleotide polymorphism (SNP) data from unrelated individuals, developed by Mass General's Psychiatric & Neurodevelopmental Genetics Unit. Learn more about it in the article "Massively Expedited Genome-wide Heritability Analysis (MEGHA),” published in the Proceedings of the National Academy of Sciences of the Unite States of America.

Download the program

For more information or help with the program, please contact Tian Ge (TGE1@partners.org).