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Research Spotlight: Multiomic Landscape of the Human Placenta at Molecular Resolution

Researchers generated the largest and most comprehensive spatially resolved single-cell census and molecular architecture of the first trimester human placenta.

How a Chance Encounter Led One Mass General Researcher on a Decade Long Journey of Discovery

For Alexander Marneros, MD, PhD, a dermatologist and researcher at Massachusetts General Hospital, a decade-long journey of discovery began with a chance encounter on his way to lunch.

Scientists Solve Mystery of How a Rare Congenital Scalp Defect Forms

Researchers have revealed the mechanisms behind mutations that cause a congenital condition called aplasia cutis congenita, in which babies are born without skin along the midline of the scalp.

Research Spotlight: How a Protein Called IKAROS Organizes the Genome in Nuclear Space to Control Healthy B Cell Development

IKAROS helps to

Research Spotlight: How IKAROS Organizes the Genome in Nuclear Space to Control Healthy B Cell Development

Scientists show how a protein called IKAROS helps

Researchers Identify the Hormone that Drives Fatigue After Cancer Radiation Therapy

A team led by scientists at Massachusetts General Hospital (MGH) recently found that the skin produces the hormone β-endorphin in response to radiation therapy, and that elevated β-endorphin levels contribute to fatigue after treatment.

Novel immunotherapy mechanism suppresses breast cancer development

CD4+ T helper 2 cells force breast cancer cells to revert to benign breast gland cells.

Skin drug treatments may regress dangerous birthmarks and prevent melanoma

Skin drug treatments may regress dangerous birthmarks and prevent melanoma. Skin drug treatments may regress dangerous birthmarks and prevent melanoma. Key Takeaways • Researchers have developed preclinical models of a condition characterized by

Researchers identify key regulators of urinary concentration in the kidney

Researchers identify key regulators of urinary concentration in the kidney. Researchers identify key regulators of urinary concentration in the kidney. Key Takeaways • The kidney carries out important functions via microscopic functional units

Study reveals how to activate natural killer cells to protect against cancer and other diseases

Scientists discover that certain proteins surrounding organs and tissues switch off natural killer cells’ “killer” function. Blocking these interactions could re-activate the cells.