NewsletterJan | 21 | 2025
A randomized three-year clinical trial recently released shows fish oil high in omega-3 fatty acids provides statistically significant benefit for those genetically predisposed to Alzheimer’s. McCance Center’s Dr. Gene Bowman is senior corresponding author.
"This is the first dementia prevention trial to use modern prevention tools, such as a blood test and brain scan to identify not only people at high risk for dementia but also what features determine response to a specific nutritional intervention," said Dr. Bowman. "The fact that neuronal integrity breakdown was slowed in people randomized to omega-3 treatment who are also at high genetic risk for Alzheimer’s disease is remarkable and warrants a larger clinical trial in more diverse populations in the future."
Bowman is head of the McCance Center Clinical Trials Platform and Brain Nutrition Laboratory and previously worked at OHSU, where he secured federal funding to conduct the clinical trial.
The journal, Nature recently published The History of Alzheimer’s Disease, with a timeline from 1906 – 2024. Three key discoveries from McCance Center Director Dr. Rudy Tanzi’s lab are featured in the chronology in 1987,1995 and 2008.
The McCance Center has launched an ambitious program to prevent Alzheimer’s disease (AD) – “The Pre-AD Initiative” (Prediction and Prevention of Alzheimer’s Disease).
Researchers have learned more about how increased levels of an enzymatic protein called HDAC6 connects to the onset of harmful brain changes in Alzheimer’s disease (AD) and identified a potential treatment strategy.
Jonathan Rosand, MD, MSC, presented the McCance Center’s strategy, strengths and progress and the Brain Care Score at the Science Summit of the 78th United Nations General Assembly meetings in New York City.
The goal of REACH-ICH is to explore how social determinants of health (SDOH) affect participation in a BP management program throughout ICH recovery.
New findings offer strong support for developing irisin as a therapeutic target for Alzheimer’s disease treatment and prevention.
Our mission is to reduce suffering and maximize human potential through better brain health for all.
