Research Spotlight: Comparison of Single-Cell Profiling Methods Reveals Strengths and Limitations
The findings will help researchers more efficiently approach projects employing single cell RNA analysis on human biopsy samples.
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188 results
Research Spotlight: Simulation Model Shows Potential Affordability of Preventative HIV Therapy for Infants
Despite efforts to improve early maternal HIV diagnosis and increase accessibility of antiretroviral therapy to reduce the risk of transmission from 30% to less than 5%, about 130,000 children acquired HIV globally in 2023.
Research Spotlight: Projecting the Impact of Funding Cuts to the President’s Emergency Plan for AIDS Relief (PEPFAR)
Researchers found that eliminating PEPFAR would lead to 601,000 HIV-related deaths, 565,000 new HIV infections, and would increase population-level healthcare expenditure by $1.7 billion.
Research Spotlight: A Narrative Review of Medical Gaslighting
Researchers aimed to provide a starting point for future research into how gaslighting may present itself, what contributes to its occurrence and how to mitigate its impacts while considering the perspectives of both patients and providers.
Pressure Check: Testing a Unique Community-Based Approach to Managing High Blood Pressure
Uncontrolled blood pressure puts people at increased risk of developing heart disease, brain disease, and kidney disease, yet only one in four people have their blood pressure under good control.
Research Spotlight: Identifying New Treatments for Pediatric Brain Cancer
Rakesh Jain PhD, Director of the E.L. Steele Laboratories for Tumor Biology at Massachusetts General Hospital and A. Werk Cook Professor of Radiation Oncology at Harvard Medical School, is senior author of a new study in PNAS, Targeting EPHB2/ABL1 Restores Anti-Tumor Immunity in Preclinical Models of Ependymoma.
Research Spotlight: Comparing the GI Side Effects of Four Medications for Alcohol Use Disorder
Researchers found that injectable naltrexone had the fewest reported GI and liver-related side effects compared to the other drugs.
Research Spotlight: How Microbes in the Human Gut Swap Genetic Traits
Researchers found that genetic swaps in the gut microbiome are occurring much more frequently than previously thought and detected more than 100,000 swaps that hadn’t been seen before.
Research Spotlight: Interplay Between Immune Cells and HPV Keeps Skin Healthy
Shadmehr (Shawn) Demehri, MD, PhD, of the Department of Dermatology and Center for Cancer Immunology at Massachusetts General Hospital, is the corresponding author of a paper published in Cancer Cell, “Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin.”
Improving Liver Cancer Outcomes Through Enhanced Immunotherapy
Dan G. Duda, DMD, PhD, of the Edwin L. Steele Laboratories for Tumor Biology and Department of Radiation Oncology at Massachusetts General Hospital, is the corresponding author of a paper published in Cancer Immunology Research, “Combination CXCR4 and PD1 Blockade Enhances Intratumoral Dendritic Cell Activation and Immune Responses Against Hepatocellular Carcinoma.”
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