About Rachel Huckfeldt, MD, PhD

Departments, Centers, & Programs:

Clinical Interests:

Treats:

Locations

Mass Eye and Ear
243 Charles St.
Boston, MA 02114
Phone: 617-523-7900

Medical Education

  • MD, Washington University
  • Residency, Massachusetts Eye and Ear
  • Fellowship, Massachusetts Eye and Ear
  • Fellowship, University of Iowa Hospitals & Clinics

American Board Certifications

  • Ophthalmology, American Board of Ophthalmology

Research

Dr. Huckfeldt’s clinically-oriented research focuses on improving the care and visual outcomes of patients with inherited retinal diseases (IRDs). Her current research focuses on understanding pathways leading to retinal degeneration and improving the clinical care of patients with retinitis pigmentosa-associated cystoid macular edema.  These projects have the potential to increase our understanding of RP and other inherited orphan retinal degenerations.  Dr. Huckfeldt also leads Mass Eye and Ear’s participation in a number of clinical trials assessing gene therapies for the treatment of IRDs.

Publications

  • 1. Huckfeldt RM, Vavvas DG. Progressive Maculopathy After Discontinuation of Pentosan Polysulfate Sodium. Ophthalmic Surg Lasers Imaging Retina. 2019 Oct 01; 50(10):656-659. 

    2. Stanwyck LK, Place EM, Comander J, Huckfeldt RM, Sobrin L. Predictive value of genetic testing for inherited retinal diseases in patients with suspected atypical autoimmune retinopathy. Am J Ophthalmol Case Rep. 2019 Sep; 15:100461.

    3. Gupta PR, Huckfeldt RM. Gene therapy for inherited retinal degenerations: initial successes and future challenges. J Neural Eng. 2017 10; 14(5):051002.

    4. Huckfeldt RM, Comander J. Management of Cystoid Macular Edema in Retinitis Pigmentosa. Semin Ophthalmol. 2017; 32(1):43-51.

    5. Ramachandran PS, Lee V, Wei Z, Song JY, Casal G, Cronin T, Willett K, Huckfeldt R, Morgan JI, Aleman TS, Maguire AM, Bennett J. Evaluation of Dose and Safety of AAV7m8 and AAV8BP2 in the Non-Human Primate Retina. Hum Gene Ther. 2017 02; 28(2):154-167.

    View more

Reviews: Comments and Ratings

4.9out of 5(130 Ratings, 48 Comments)

March 2025

Dr. Rachel Huckfeldt is an amazing provider with clarity, gentleness and compassion. I always feel, along with my wife, that we always are at ease in her presence as she explains all that needs to be detailed with my retinitis pigmentosa. God bless you always. Thanks so much.


March 2025

Professional and thorough


March 2025

Provider was incredibly competent , caring , professional , understanding , compassionate. The best of the best . Bed side manner second to none


March 2025

Every went well same usually it is all good thanks


March 2025

Dr. Huckfeldt is a great doctor, explains everything in depth so that you can understand it, really shows that she cares about your vision and about a plan going forward. I would recommend her to anybody who has retinitis pigmentosa.


March 2025

The IRD team at MEEI is amazing and we are so fortunate to have them in the Boston area! They are not only subject matter experts, they are very understanding of the challenges of their patients!


March 2025

It was a great experience. I enjoyed it. Thank you.


February 2025

Well, I say well and they treat everything very well, not even the nurses, the doctors, all the specialists, everything is a nice care, thank you.


February 2025

This was the first & probably only time seeing this provider. She provided me with a large amount on info that will take me some time to adjust to in order to share info with family as needed. I can't think of any easy way for all that was discussed to be shared. Time for me to "put my brain in gear" to absorb this unfamiliar medical ... Read More


January 2025

Dr Huckfeldt was professional, knowledgeable and worked well and courteously with her fellow to explain my results and discuss nuances of my concerns. Tremendous work.

View More
Ratings and Comments Powered by NRC Health