About Steven Isakoff, MD, PhD, MMSC

Departments, Centers, & Programs:

Clinical Interests:

Treats:

Locations

Mass General Cancer Center: Hematology Oncology
55 Fruit St.
Boston, MA 02114
Phone: 617-726-6500
Fax: 617-724-1079

Medical Education

  • MD, New York University School of Medicine
  • Residency, Brigham and Women's Hospital
  • Fellowship, Dana Farber Cancer Institute

American Board Certifications

  • Medical Oncology, American Board of Internal Medicine

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Publications

  • Isakoff SJ, Tabernero J, et al. Antitumor activity of ipatasertib combined with chemotherapy: results from a phase Ib study in solid tumors. Ann Oncol. 2020 May Xu J,..., Isakoff SJ. A Phase II Trial of Cabozantinib in Hormone Receptor-Positive Breast Cancer with Bone Metastases. Oncologist. 2020 AugKoh SB, Ross K, Isakoff SJ, ... Ellisen LW. RASAL2 Confers Collateral MEK/EGFR Dependency in Chemoresistant Triple-Negative Breast Cancer. Clin Cancer Res. 2021 Sep 1Dent R, Oliveira M, Isakoff SJ, et al; LOTUS investigators. Final results of the double-blind placebo-controlled randomized phase 2 LOTUS trial of first-line ipatasertib plus paclitaxel for inoperable locally advanced/metastatic triple-negative breast cancer. Breast Cancer Res Treat. 2021 Sep Coates JT, Sun S, ... Isakoff SJ,...Ellisen LW. Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer. Cancer Discov. 2021 Aug 17.Xu J,...Isakoff SJ. Phase II trial of veliparib and temozolomide in metastatic breast cancer patients with and without BRCA1/2 mutations. Breast Cancer Res Treat. 2021 Aug 20.

Reviews: Comments and Ratings

5.0out of 5(171 Ratings, 67 Comments)

January 2025

Knowledgeable, caring, takes time


January 2025

Dr. Isakoff was very patient with us. He spent a very long time with us answering all of our questions. He was incredibly thorough. He asked me about, you know, things unrelated to my cancer and just made us feel comfortable and safe. It was a very helpful consultation, and I left feeling in control and optimistic about how things would go.


January 2025

Dr. Isakoff is the best


January 2025

I can not say enough about Dr. Isakoff. From day one with my diagnosis to 10 years later, he is always amazing. Brilliant and kind. Patient, and knowledgeable. I am grateful for him.


January 2025

I've been a patient of Dr. Isakoff for the past 11 years and can't imagine having a better doctor to be under his care. He's very thoughtful, gives me plenty of time to talk, and is very thorough with his examinations. And I really can't say enough great things about Dr. Isakoff and would highly, highly recommend him to anyone that's going through ... Read More


January 2025

Dr Isakoff has an excellent bed side manner! I appreciate how he makes me feel comfortable.


January 2025

As usually Dr Isakoff was helpful, listened to my concerns, personable and veet professional


December 2024

Excellent


December 2024

Absolutely fabulous, fantastic, professional, knowledgeable, caring, the best.


November 2024

He is helpful and he knows my medical history very well and was able to explain things very clearly. I would recommend him to any of my family friends, even people I don't know. Thank you.

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