About Kenneth Tanabe, MD

Clinical Interests:

Treats:

Locations

Mass General Surgery: Surgical Oncology
55 Fruit St.
Yawkey Center for Outpatient Care
7th Floor
Boston, MA 02114
Phone: 617-724-4000

Mass General Cancer Center in Waltham
52 Second Ave.
Suite 1110
Waltham, MA 02451
Phone: 781-487-6100

Medical Education

  • MD, University of California San Diego
  • Residency, New York Presbyterian - Weill Cornell Medical Center
  • Fellowship, The University of Texas - M.D. Anderson Cancer Center

American Board Certifications

  • Surgery, American Board of Surgery

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Research

Dr. Tanabe directs a research laboratory focused on 1) hepatocellular carcinoma prevention; and 2) experimental gene therapy for liver tumors. His laboratory has been funded by the National Institutes of Health continuously since 1993.

Research in the area of hepatocellular carcinoma focuses on signal transduction pathways involved during malignant transformation of hepatocytes, and molecular mechanisms of cirrhosis progression. Agents that prevent progression of cirrhosis or prevent development of hepatocellular carcinoma in cirrhotic livers are examined in preclinical models before development of clinical trials. The effects on liver are monitored via a gene signature, in collaboration with Yujin Hoshida and Todd Golub at the Broad Institute.

Research in experimental gene therapy for liver tumors focuses on development of replication-conditional viruses that destroy tumors by virtue of replication in the tumor cells, a process that simultaneously produces daughter progeny virion that can infect adjacent tumor cells. Significant progress has been made in alteration of the viral genome to restrict viral replication in normal cells. One virus is now in clinical trial for patients with primary or secondary liver tumors.

Publications

Reviews: Comments and Ratings

4.9out of 5(139 Ratings, 64 Comments)

February 2025

[redacted] When Dr. Tanabe came into the room he never introduced himself so I introduced myself. He asked why I was there I started to tell him and he looked away and focused on the computer. No face to face contact he was busty typing. Very brisk demeanor. I did not feel comfortable asking questions. [redacted] I'm not expecting hand holding but ... Read More


January 2025

I have the greatest respect for Dr. Tanabe. I am very grateful that he was my surgeon. I always look forward to follow-up visits with him.


January 2025

Dr Tanabe was very professional, understanding and compassionate. He explained everything to me in a way I could understand. He made me feel very at ease.


December 2024

Superb melanoma surgeon


December 2024

Dr. Tanabe was absolutely wonderful. I was extremely worried before coming in and he was very reassuring and put me at ease. After my exam he took time to explain everything about my diagnosis and surgery so that I left the office feeling well informed and ready to go forward.


December 2024

My Doctor is extremely efficient, polite, interested, and I feel very lucky to have him.


December 2024

Dr Tanabe, He is amazing. He saved my life and I will Always be grateful for his expert care.


December 2024

I was surprised there is a possibility of a cancer tumor but it was all explained thoroughly once in the appointment


December 2024

A truly outstanding physician!!


December 2024

Great surgeon

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