About Carlos Fernandez-del Castillo, MD

Dr. Carlos Fernandez-del Castillo is a gastrointestinal surgeon specialized in pancreatic and biliary diseases.

Dr. Fernandez-del Castillo is the director of the pancreas and biliary surgery program and clinical co-director of the GI cancer center at the MGH, as well as professor of surgery at Harvard Medical School. He is a widely recognized expert in pancreatic and biliary surgery, and has authored over 350 publications on pancreatic cancer, cystic tumors of the pancreas, Intraductal papillary mucinous neoplasms (IPMN), neuroendocrine pancreatic tumors, acute and chronic pancreatitis. For several years he has performed the largest number of pancreatic resections in New England.  He serves in the editorial board many journals, including Annals of Surgery and Pancreatology, and is a past president of the American Pancreatic Association.

Clinical Interests:

Treats:

Languages:

Locations

Massachusetts General Hospital
55 Fruit St.
Boston, MA 02114
Phone: 617-726-5644

Medical Education

  • MD, Universidad Nacional Autonoma De Mexico
  • Residency, Instituto Nacional de la Nutricion
  • Fellowship, Massachusetts General Hospital

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Research

Dr. Fernandez-del Castillo has laboratory and clinical research focused on pathogenesis of acute pancreatitis, models of pancreatic cancer, molecular genetics of pancreatic cancer and cystic neoplasms of the pancreas, and neuroendocrine tumors.

Publications

  • Select Publications:

    • Phase I Study of Preoperative Short-Course Chemoradiation with Proton Beam Therapy and Capecitabine for Resectable Pancreatic Ductal Adenocarcinoma of the Head. Hong TS, Ryan DP, Blaszkowsky LS, Mamon HJ, Kwak EL, Mino-Kenudson M, Adams J, Yeap B, Winrich B, Delaney TF, Fernandez-Del Castillo C. Int J Radiat Oncol Biol Phys. 2010 Apr 24.
    • Invasive intraductal papillary mucinous carcinomas of the pancreas: predictors of survival and the role of lymph node ratio. Partelli S, Fernandez-Del Castillo C, Bassi C, Mantovani W, Thayer SP, Crippa S, Ferrone CR, Falconi M, Pederzoli P, Warshaw AL, Salvia R. Ann Surg. 2010 Mar;251(3):477-82.
    • New metastatic lymph node ratio system reduces stage migration in patients undergoing D1 lymphadenectomy for gastric adenocarcinoma. Maduekwe UN, Lauwers GY, Fernandez-Del-Castillo C, Berger DL, Ferguson CM, Rattner DW, Yoon SS.  Ann Surg Oncol. 2010 May;17(5):1267-77. Epub 2010 Jan 23.
    • Pancreatic cysts: preoperative diagnosis and clinical management. Pitman MB, Lewandrowski K, Shen J, Sahani D, Brugge W, Fernandez-del Castillo C. Cancer Cytopathol. 2010 Feb 25;118(1):1-13. Review.
    • Pancreatic duct glands are distinct ductal compartments that react to chronic injury and mediate Shh-induced metaplasia. Strobel O, Rosow DE, Rakhlin EY, Lauwers GY, Trainor AG, Alsina J, Fernández-Del Castillo C, Warshaw AL, Thayer SP. Gastroenterology. 2010 Mar;138(3):1166-77. Epub 2009 Dec 21.

Reviews: Comments and Ratings

4.9out of 5(254 Ratings, 110 Comments)

March 2025

Dr Fernandez is caring, supportive, compassionate and very knowledgeable. He had carefully reviewed my recent test and explained the results to me in a clearly understandable manner. He listened to my concerns and carefully explained the follow up plan.


March 2025

I am grateful to be able to see this outstanding, fabulous physician at the incredible facilities and operating excellence of Mass General. Having transitioned from private, employer based insurance to Medicare Part A &B during my care I applaud and appreciate you for a seamless financial transition. Many thanks!


February 2025

I had an excellent experience with Dr. Fernandez del Castillo and also his residents, and I feel very confident going into surgery with Dr. Fernandez performing the surgery, and I certainly feel that it was a very positive experience and would certainly recommend him to anyone who is facing surgery. And both he and his residents explained things ... Read More


February 2025

Dr. Fernandez is wonderful! Very knowledgeable and helpful


February 2025

He's very respectful and very clear and very professional and takes a special interest.


February 2025

Exceptional experience. Respectful, informative and with an outreach to my comprehension level. I felt very well cared for by both people in attendance.


February 2025

I love Dr Carlos Fernandez-Del Castillo! He is an amazing doctor/surgeon, a phenomenal asset to MGH and very intelligent in his field. He has a great personality & concern for his patients. One of the Best!


February 2025

He is kind caring articulate. Although his reputation precedes him, i found him very approachable and down to earth. He was succinct and cogent. Couldnt have hoped for more. Same with his resident max brisky. They made me comfortable with the information treated me with kindness and gave me great confidence that i am in great hands


February 2025

I experienced an issue while in the exam room and the doctor was there to ensure that I was well looked after and take a care of by himself and the entire support staff


January 2025

I appreciate the continuity of having him as my doctor for all the years of my care, since 2008. I feel comfortable in my interactions with him and trusting of his knowledge and skills.

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