Approved Drug May Be Repurposed to Treat Tumors Resulting from NF2-Related Schwannomatosis
Clinical trial generates promising results for brigatinib as a treatment for the genetic condition, which is characterized by brain and nerve sheath tumors.
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Mass General Cancer Center Researchers Identify Gene That Helps Cancer Cells Spread Throughout the Body
The findings could lead to new strategies to treat metastatic cancer and would be particularly impactful for patients with pancreatic cancer.
Patient Stories: CDH1 Gene Mutation—Gretchen | Massachusetts General Hospital
The discovery of a CDH1 gene mutation in the family led Gretchen Borzi on a journey of genetic testing and preventative surgery with a multidisciplinary team. Learn more.
Trial Reveals Benefits of ‘Stepped’ Palliative Care for Patients with Advanced Lung Cancer
Patients with advanced lung cancer who received stepped palliative care reported similar quality of life (QOL) scores as those who received monthly palliative care visits from the time of diagnosis.
Research Spotlight: Long-Coding RNAs Act as Scaffolds for Assembling Heterochromatin
Mo Motamedi, PhD, an assistant investigator in the Mass General Cancer Center and an assistant professor of Medicine at Harvard Medical School, is the James & Patricia Poitras Endowed Chair in Cancer Research and the senior author of a new paper in Cell, RNA Quality Control Factors Nucleate Clr4/SUV39H and Trigger Constitutive Heterochromatin Assembly.
Statin Therapy May Prevent Cancer by Blocking Inflammatory Protein
A team led by investigators from Mass General Cancer Center found that statins—commonly used cholesterol-lowering drugs—may block a pathway that leads to the development of cancer in the context of chronic inflammation.
Mass General Cancer Center Researchers Present Key Findings at ASCO
Leaders from the Mass General Cancer Center will present research discoveries and outcomes from clinical trials in cancer at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, held May 31-June 4, in Chicago.
Research Spotlight: Aging Weakens T Cells in the Tumor Microenvironment Making Them Less Effective at Fighting Cancer
The findings encourage researchers to further test whether the mRNA cancer vaccine can be used in combination with other therapies to improve therapeutic outcomes.
Research Spotlight: A Better Understanding of Immune Checkpoint Inhibitor-Related Colitis
This study was designed to investigate which cellular, transcriptional and signaling programs are associated with the development of colitis in cancer patients being treated with immune checkpoint inhibitors (ICIs).
New Mammogram Guidelines | Massachusetts General Hospital
The U.S. Preventive Services Task Force now recommends women start getting mammograms at age 40, as breast cancer rates are increasing in younger women.
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