Statin Therapy May Prevent Cancer by Blocking Inflammatory Protein
Study results indicate that pitavastatin inhibits an inflammatory pathway that in turn can suppress skin and pancreatic cancers.
Contact Information
Boston, MAPhone: 617-726-2914
Video: Meet Dr. Demehri and learn about melanoma
Shawn Demehri, MD, PhD is a board-certified dermatologist and a Principal Investigator at the Center for Cancer Immunology and Cutaneous Biology Research Center of Massachusetts General Hospital. Dr. Demehri attended Washington State University, where he obtained his bachelor’s degree in biology with honors. He received his medical (MD) and PhD degree in cell and molecular biology from Washington University in St. Louis. After completing his internship, Dr. Demehri completed a combined dermatology residency and postdoctoral fellowship in immunology at Washington University, twice receiving research fellowship awards from the Dermatology Foundation and American Skin Association.
Dr. Demehri is a recipient of American Academy of Dermatology Young Investigator Award and Burroughs Wellcome Fund Career Award for Medical Scientists and NIH Director's Early Independence Award. He has numerous peer-reviewed publications in reputable journals and has presented his work at the Society for Investigative Dermatology, Tumor Immunology and Gordon Research Conferences. Dr. Demehri is a physician-scientist performing basic science and translational research in the area of cancer immunology related to melanoma and non-melanoma skin cancers.
His research is focused on determining the role of the immune system in preventing the early stages of cancer development. Dr. Demehri’s clinical interests include cutaneous oncology with a focus on the detection and treatment of high-risk skin cancers, inflammatory skin diseases that predispose patients to skin cancer, skin cancer prevention and general dermatology.
For more information, please visit the Demehri Laboratory website.
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Mass General Dermatology
50 Staniford St.
Boston, MA 02114
Phone: 617-726-2914
Medical Education
American Board Certifications
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The Adolescent and Young Adult Cancer Program was created to optimize the care, outcomes, and experiences of adolescent and young adult patients.
Mass General is recognized as a top hospital on the U.S. News Best Hospitals Honor Roll for 2024-2025.
Study results indicate that pitavastatin inhibits an inflammatory pathway that in turn can suppress skin and pancreatic cancers.
While carcinogens are widely known to be perpetrators of cancer, a new study from researchers at the Mass General Cancer Center has shown that exposure to carcinogens can increase cancer cells’ susceptibility to immune attack.
The findings point to a new treatment strategy to improve immune-based treatments for basal cell carcinoma.
A new study by investigators from Mass General Brigham uncovers how a novel immunotherapy prevents squamous cell carcinoma, with benefits lasting five years after treatment.
Shawn Demehri, MD, PhD, director of the Massachusetts General Hospital High Risk Skin Cancer Clinic, discusses the risk factors for basal cell carcinoma, the signs of skin cancer, and prevention tips that can help you protect your skin all year round.
Shadmehr (Shawn) Demehri, MD, PhD, is the corresponding author of a paper published in Cancer Cell, “Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin.”
Study results indicate that pitavastatin inhibits an inflammatory pathway that in turn can suppress skin and pancreatic cancers.
While carcinogens are widely known to be perpetrators of cancer, a new study from researchers at the Mass General Cancer Center has shown that exposure to carcinogens can increase cancer cells’ susceptibility to immune attack.
The findings point to a new treatment strategy to improve immune-based treatments for basal cell carcinoma.
A new study by investigators from Mass General Brigham uncovers how a novel immunotherapy prevents squamous cell carcinoma, with benefits lasting five years after treatment.
He is professional & personable. I feel comfortable in his care
very professional
Great doctor
Thank you. I really appreciated Dr. Shad Demehri seeing me and his attention was excellent. I also would like to note that the phone intake, as I am a new patient, by the person who took my information over the phone was absolutely excellent and I appreciate both my in-person visits and my online intake. Thank you very much.
Very knowledgeable and skillful.
Excellent care and many thanks, [redacted]
Dr Demehri is the only doctor out of five dermatologists who explained why I was getting so many squamous cell cancers on my lower legs and what I could do to prevent it. AND HIS TREATMENT PLAN WORKS!! After so many excisions it has finally stopped. Dr Demehri is THE BEST!!
Excellent communication and treatment
They are very polite and kind.
the care provider was extremely knowledgeable and dedicated to his professional mission which is not only to treat but mostly to recommend prevention In my avoiding any long term exposure to potentially cancer causing lifestyles from sun exposure.