About Steven Isakoff, MD, PhD, MMSC

Departments, Centers, & Programs:

Clinical Interests:

Treats:

Locations

Mass General Cancer Center: Hematology Oncology
55 Fruit St.
Boston, MA 02114
Phone: 617-726-6500
Fax: 617-724-1079

Medical Education

  • MD, New York University School of Medicine
  • Residency, Brigham and Women's Hospital
  • Fellowship, Dana Farber Cancer Institute

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Publications

  • Isakoff SJ, Tabernero J, et al. Antitumor activity of ipatasertib combined with chemotherapy: results from a phase Ib study in solid tumors. Ann Oncol. 2020 May Xu J,..., Isakoff SJ. A Phase II Trial of Cabozantinib in Hormone Receptor-Positive Breast Cancer with Bone Metastases. Oncologist. 2020 AugKoh SB, Ross K, Isakoff SJ, ... Ellisen LW. RASAL2 Confers Collateral MEK/EGFR Dependency in Chemoresistant Triple-Negative Breast Cancer. Clin Cancer Res. 2021 Sep 1Dent R, Oliveira M, Isakoff SJ, et al; LOTUS investigators. Final results of the double-blind placebo-controlled randomized phase 2 LOTUS trial of first-line ipatasertib plus paclitaxel for inoperable locally advanced/metastatic triple-negative breast cancer. Breast Cancer Res Treat. 2021 Sep Coates JT, Sun S, ... Isakoff SJ,...Ellisen LW. Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer. Cancer Discov. 2021 Aug 17.Xu J,...Isakoff SJ. Phase II trial of veliparib and temozolomide in metastatic breast cancer patients with and without BRCA1/2 mutations. Breast Cancer Res Treat. 2021 Aug 20.

Reviews: Comments and Ratings

4.9out of 5(167 Ratings, 73 Comments)

February 2025

Dr. Isakoff always takes plenty of time with me, not only talking to me about my cancer and oncology needs, but also is very thoughtful about asking about my life, my family, how I'm feeling, anything new going on, and I just feel like he's a very caring provider.


February 2025

Dr. Isakoff is the kind of doctor that everyone wishes they had. I feel like I am in good hands.


February 2025

I am really pleased with Dr. Isakoff and his staff! Excellent service!


February 2025

He is the one of best provider that I knew. He helped me when I most needed with my breast cancer treatments and continue with my health issue from cancer treatment. I will highly recommend him to anyone who need help with breast cancer.


February 2025

Excellent experience


February 2025

Dr. Isakoff is brilliant, kind, respectful & a great listener. Couldn't be in better hands!


February 2025

Dr. Isakoff is an outstanding oncologist and person. I value my time with him and his heed his treatment advise. He is an MGH asset and super star.


February 2025

I have complete faith in Dr. Isakoff. He has taken care of me for ten years. Will continue to check in with him each year after my mammograms


February 2025

I feel very fortunate. Dr. Isakoff and Dr. [redacted] were very kind and understanding. I really felt heard and cared for.


February 2025

Dr. Isakoff takes the time to listen and explain carefully. He remembers my health history and is sensitive to my concerns.

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