About Kenneth Tanabe, MD

Clinical Interests:

Treats:

Locations

Mass General Surgery: Surgical Oncology
55 Fruit St.
Yawkey Center for Outpatient Care
7th Floor
Boston, MA 02114
Phone: 617-724-4000

Mass General Cancer Center in Waltham
52 Second Ave.
Suite 1110
Waltham, MA 02451
Phone: 781-487-6100

Medical Education

  • MD, University of California San Diego
  • Residency, New York Presbyterian - Weill Cornell Medical Center
  • Fellowship, The University of Texas - M.D. Anderson Cancer Center

American Board Certifications

  • Surgery, General, American Board of Surgery

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Research

Dr. Tanabe directs a research laboratory focused on 1) hepatocellular carcinoma prevention; and 2) experimental gene therapy for liver tumors. His laboratory has been funded by the National Institutes of Health continuously since 1993.

Research in the area of hepatocellular carcinoma focuses on signal transduction pathways involved during malignant transformation of hepatocytes, and molecular mechanisms of cirrhosis progression. Agents that prevent progression of cirrhosis or prevent development of hepatocellular carcinoma in cirrhotic livers are examined in preclinical models before development of clinical trials. The effects on liver are monitored via a gene signature, in collaboration with Yujin Hoshida and Todd Golub at the Broad Institute.

Research in experimental gene therapy for liver tumors focuses on development of replication-conditional viruses that destroy tumors by virtue of replication in the tumor cells, a process that simultaneously produces daughter progeny virion that can infect adjacent tumor cells. Significant progress has been made in alteration of the viral genome to restrict viral replication in normal cells. One virus is now in clinical trial for patients with primary or secondary liver tumors.

Publications

Reviews: Comments and Ratings

4.8out of 5(138 Ratings, 61 Comments)

March 2025

Dr. Tanabe was wonderful


March 2025

Doctor Tanabe was very caring and explained just what needed to be done and calmed my nerves. I highly recommend him and appreciate his caring compassion.


March 2025

I'm very impressed with Dr. Tanabe's communication and his manner. Very comfortable with him. I feel very well informed. He called today on a Saturday to give me an update on discussions and plans for the surgery and to answer any questions I had. So I'm very pleased about that.


March 2025

Yes, Dr. Tanabe was outstanding. He clearly knows what he's doing and puts the patient at ease.


February 2025

Oh yes, I was apprehensive going into the office. I was less apprehensive coming out because the outcome I expected was much better than I had anticipated. That's probably the most I can say about the visit. It was very concise and explained what would be done, what he would do, and what the plastic surgeon would do. And just to take one day at a ... Read More


February 2025

He was friendly, kind and direct. He explained things in a manner easy to understand. He answered all my questions as well


February 2025

I absolutely love Dr. Tanabe and his staff. Everybody is very thoughtful and kind. Dr. Tanabe is very personable, and you can tell he's confident in his knowledge, and understanding of the medical problems in front of him. I trust him, which is really important, especially with what kind of case he handles. And he's very genuine. He's constantly ... Read More


February 2025

[redacted] When Dr. Tanabe came into the room he never introduced himself so I introduced myself. He asked why I was there I started to tell him and he looked away and focused on the computer. No face to face contact he was busty typing. Very brisk demeanor. I did not feel comfortable asking questions. [redacted] I'm not expecting hand holding but ... Read More


January 2025

I have the greatest respect for Dr. Tanabe. I am very grateful that he was my surgeon. I always look forward to follow-up visits with him.


January 2025

Dr Tanabe was very professional, understanding and compassionate. He explained everything to me in a way I could understand. He made me feel very at ease.

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