Advances at Mass General Cancer Center
Recent Articles
New Treatment for Nonmetastatic Castration-Resistant Prostate Cancer
New research by Matthew Smith, MD, PhD, director of the Genitourinary Malignancies Program and colleagues has identified a therapy, apalutamide, that can delay the spread of cancer in nmCRPC patients.
Extracellular Vesicles in Brain Cancer Blood Testing
In this study, Shannon Stott, PhD and Brian Nahed, MD, MSc describe a technique of microfluidics and nanosurfaces to capture EVs released from glioblastoma multiforme, a form of brain cancer.
Transit of Tumor Cells Through Lymph Node Vasculature
Researchers Timothy P. Padera, PhD and Ethel R. Pereira, PhD have used intravital microscopy and photoconvertible proteins to label cancer cells, whose migration through the body can then be tracked.
Podcast Series
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This podcast is a companion to Mass General Cancer Center’s electronic publication, and both are centered around our investigators' recent publications in high-profile journals. Each expert will give you insight into who they are and what inspires them to do what they do every day. A deeper dive into their research will better your understanding of where our experts’ ideas come from, where they will go from here, and what the future has in store in their particular field of research.
iTunes Episode Library
- Episode 01: Getting to Know Raul Mostoslavsky, MD, PhD
- Episode 02: New Therapeutic Targets for Pancreatic Cancer with Raul Mostoslavsky, MD, PhD
- Episode 03: The Future of Epigenetic Research with Raul Mostoslavsky, MD, PhD
- Episode 04: Getting to Know Nir Hacohen, PhD
- Episode 05: Immunology: Paving the Way to New Cancer Treatments with Nir Hacohen, PhD
- Episode 06: The Future of Immunology in Cancer Care with Nir Hacohen, PhD
- Episode 07: Getting to Know Areej El-Jawahri, MD
- Episode 08: Palliative Care: The Potential Benefit for Patients with Areej El-Jawahri, MD
- Episode 09: The Future of Palliative Care for Curative Intent with Areej El-Jawahri, MD
- Episode 10: Getting to know Aditya Bardia, MD and Shyamala Maheswaran, PhD
- Episode 11: When HER2-positive cells switch to HER2-negative cells in Breast Cancer, with Aditya Bardia, MD and Shyamala Maheswaran, PhD
- Episode 12: The Future Direction of HER2 Cells in Breast Cancer, with Aditya Bardia, MD and Shyamala Maheswaran, PhD
- Episode 13: Getting to know Nabeel Bardeesy, PhD
- Episode 14: Epigenetic-Metabolic Pathways in Pancreatic Tumor Cells with Nabeel Bardeesy, PhD
- Episode 15: Future Directions with Nabeel Bardeesy, PhD
- Episode 16: Getting to Know Mario Suvà, MD, PhD
- Episode 17: Identifying Therapeutic Targets for IDH-Mutant Brain Tumors with Mario Suvà, MD, PhD
- Episode 18: What’s Next for Mario Suvà, MD, PhD and his Research
- Episode 19: Getting to know Lipika Goyal, MD
- Episode 20: Investigating biliary duct cancer mutations with Lipika Goyal, MD
- Episode 21: What’s next for Lipika Goyal, MD and her research?
- Episode 22: Getting to know Othon Iliopoulos, MD
- Episode 23: Combination Therapy for Renal Cell Carcinoma with Othon Iliopoulos, MD
- Episode 24: What’s next for Othon Iliopoulos, MD and his research?
- Episode 25: Getting to know Priscilla Brastianos, MD
- Episode 26: New Genetic-Based Treatment for Glioneuronal Tumors with Priscilla Brastianos, MD
- Episode 27: What’s Next for Priscilla Brastianos, MD, and her clinical trials
- Episode 28: Getting to know Nir Hacohen, PhD
- Episode 29: Immune Checkpoint Blockade Therapy in Metastatic Melanoma with Nir Hacohen, PhD
- Episode 30: Nir Hacohen, PhD on what’s next for immunotherapy research and therapies
- Episode 31: Getting to know Miguel Rivera, MD
- Episode 32: Activation of Ewing Sarcoma oncogenes with Miguel Rivera, MD
- Episode 33: What’s next for Miguel Rivera, MD and his team
- Episode 34: Getting to know Lee Zou, PhD
- Episode 35: ATR Inhibition in Tumor Cells with Lee Zou, PhD
- Episode 36: What’s next for Lee Zou, PhD and his team
- Episode 37: Getting to know Ryan Corcoran, MD, PhD
- Episode 38: Divergent Resistance Mechanisms in Metastases with Ryan Corcoran, MD, PhD
- Episode 39: What’s next for Ryan Corcoran, MD, PhD, his team, and their research
- Episode 40: Getting to know David Miyamoto, MD, PhD
- Episode 41: New Blood-Based Monitoring of Prostate Cancer with David Miyamoto, MD, PhD
- Episode 42: The Future of David Miyamoto's and his team's research
- Episode 43: Getting to know Ethel Pereira, PhD
- Episode 44: Getting to know Tim Padera, PhD
- Episode 45: Transit Tumor Cells Through Lymph Node Vasculature with Ethel Pereira, PhD and Tim Padera, PhD
- Episode 46: The impact of the study on Transit Tumor Cells Through Lymph Node Vasculature with Ethel Pereira, PhD and Tim Padera, PhD
- Episode 47: Getting to know Shannon Stott, PhD, and Brian Nahed, MD, MSc
- Episode 48: A study on new techniques for capturing EVs released from glioblastoma with Shannon Stott, PhD, and Brian Nahed, MD, MSc
- Episode 49: The impact and next steps for research led by Shannon Stott, PhD, and Brian Nahed, MD, MSc
Meet Our Host
Nick Dyson, PhD is the Scientific Director at Mass General Cancer Center and a professor of Medicine at Harvard Medical School. Nick received his PhD from the University of Manchester and reached Boston by way of Amersham International, PLC, a health science company, and Cold Spring Harbor Laboratory. Nick is a senior scientist at Mass General Cancer Center’s Center for Cancer Research in Charlestown, Mass., where he directs a cutting-edge laboratory. Nick has made breakthroughs in our understanding of how cells divide, both the regulated division of a normal cell and the abnormal proliferation of a malignant cancer.
Article Archive
2018
- December 2018: New Treatment for Nonmetastatic Castration-Resistant Prostate Cancer
- November 2018: Extracellular Vesicles in Brain Cancer Blood Testing
- October 2018: Transit of Tumor Cells Through Lymph Node Vasculature
- September 2018: New Blood-Based Monitoring of Prostate Cancer
- July 2018: Divergent Resistance Mechanisms in Metastases
- June 2018: ATR Inhibition in Tumor Cells
- April 2018: Prion-Like Domains Drive Tumor Growth in Ewing Sarcoma
- March 2018: Beating Resistance to Immunotherapy in Metastatic Melanoma
- February 2018: New Genetic-Based Treatment for Glioneuronal Tumors
- January 2018: New Combination Therapy for Renal Cell Carcinoma
2017
- December 2017: Secondary FGFR2 Mutations Drive Drug Resistance to FGFR Inhibitors in Bile Duct Cancer
- November 2017: Identifying Therapeutic Targets for IDH-Mutant Brain Tumors
- October 2017: Epigenetic-Metabolic Pathways in Pancreatic Tumor Cells
- September 2017: Dynamic HER2 Switch Discovered in Circulating Breast Cancer Cells
- August 2017: Improved Outcomes and Palliative Care
- July 2017: Antitumor Immunity and Its Evasion by Tumors
- June 2017: A New Therapeutic Target for Pancreatic Cancer