Search Cancer Clinical Trials

Mass General Cancer Center offers patients access to a wide variety of clinical trials of promising new therapies. Use the search tool to find open protocols for your type of cancer.
12 results
  • Pancreatic Cancer, Gastric (Stomach) Cancer, Esophageal Cancer

21-385          Phase I

A PHASE 1 STUDY OF TJ033721 IN SUBJECTS WITH ADVANCED OR METASTATIC SOLID TUMORS

  • Bladder Cancer, Breast Cancer, Cervical Cancer, Ovarian Cancer, Pancreatic Cancer, Esophageal Cancer, Prostate Cancer, Head and Neck Cancer, Lung Cancer

24-114          Phase I

A Phase 1 Trial Investigating LY4101174, an Antibody-Drug Conjugate Targeting Nectin-4, in Participants with Recurrent, Advanced or Metastatic Solid Tumors

  • Esophageal Cancer, Liver Cancer, Pancreatic Cancer, Bladder Cancer, Endometrial Cancer, Sarcoma, Gastric (Stomach) Cancer

20-544          Phase II

A Phase 1/2 Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of PC14586 in Patients with Advanced Solid Tumors Harboring a p53 Y220C Mutation

  • Ovarian Cancer, Lung Cancer, Gastric (Stomach) Cancer, Esophageal Cancer, Bladder Cancer, Breast Cancer

23-679          Phase II

A Phase 1/2 Study of PRO1107 in Patients with Advanced Solid Tumors

  • Esophageal Cancer, Gastric (Stomach) Cancer

22-253          Phase II

A Phase 2 Trial to Evaluate the Safety and Efficacy of Domvanalimab (AB154) and Zimberelimab (AB122) -Based Treatment Combinations in Patients with Advanced Upper Gastrointestinal Tract Malignancies

  • Rectal Cancer, Thymoma, Ovarian Cancer, Colorectal Cancer, Esophageal Cancer, Gastric (Stomach) Cancer, Head and Neck Cancer, Kidney Cancer, Lung Cancer, Melanoma

23-423          Phase I

A Phase I, Open-label, Multi-center Study of KFA115 as a Single Agent and in Combination with Pembrolizumab in Patients with Select Advanced Cancers

  • Gastric (Stomach) Cancer, Esophageal Cancer

24-486          Phase III

A Phase III Multi-center, Open-label, Sponsor-blinded, Randomized Study of AZD0901 Monotherapy Compared with Investigator’s Choice of Therapy in Second- or Later-Line Adult Participants with Advanced/Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

  • Esophageal Cancer, Gastric (Stomach) Cancer

24-242          Phase II

A Single-Arm, Multicenter Phase 2 Study of Neoadjuvant Pembrolizumab with Trastuzumab and Chemotherapy in Resectable HER2+ Esophagogastric Tumors

  • Esophageal Cancer, Lung Cancer, Gastric (Stomach) Cancer, Colorectal Cancer, Breast Cancer

22-499          Phase I

An Open-label, Multicenter, Phase 1, First in Human, Dose Escalation and Expansion Study of XMT-2056 in Participants with Advanced/Recurrent Solid Tumors that Express HER2

  • Gastric (Stomach) Cancer, Esophageal Cancer

23-526          Phase I

Open-label dose-finding trial to explore safety, pharmacokinetics, pharmacodynamics, and efficacy of BI 3706674 given orally as monotherapy in patients with unresectable metastatic KRAS wild type amplified gastric, oesophageal, and gastroesophageal-junction adenocarcinoma

Showing 1 - 10 of 12 results