Search Cancer Clinical Trials

Mass General Cancer Center offers patients access to a wide variety of clinical trials of promising new therapies. Use the search tool to find open protocols for your type of cancer.
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32 results
  • Vulva Cancer, Uterine Cancer, Ovarian Cancer, Cervical Cancer, Breast Cancer

24-485          Phase I

AKTive-001: A Phase 1/1b Multiple Cohort Trial of ALTA2618 in Patients with Advanced Solid Tumors with AKT1 E17K Mutation

  • Breast Cancer

23-206          Phase III

An Open Label, Randomized, Multicenter Study Comparing the Efficacy and Safety of the Combination of Lasofoxifene and Abemaciclib to the Combination of Fulvestrant and Abemaciclib for the Treatment of Pre- and Postmenopausal Women and Men with Locally Advanced or Metastatic ER+/HER2- Breast Cancer with an ESR1 Mutation

  • Colorectal Cancer, Lung Cancer, Gastric (Stomach) Cancer, Esophageal Cancer, Breast Cancer

22-499          Phase I

An Open-label, Multicenter, Phase 1, First in Human, Dose Escalation and Expansion Study of XMT-2056 in Participants with Advanced/Recurrent Solid Tumors that Express HER2

  • Breast Cancer

24-676          Phase III

Elacestrant versus Standard Endocrine Therapy in Women and Men with Node-positive, Estrogen Receptor-positive, HER2-negative, Early Breast Cancer with High Risk of Recurrence - A Global, Multicenter, Randomized, Open-label Phase 3 Study (ELEGANT)

  • Breast Cancer

19-188          Phase II

Evaluation of Talazoparib, a PARP inhibitor, in patients with somatic BRCA mutant metastatic breast cancer: genotyping based clinical trial

  • Ovarian Cancer, Head and Neck Cancer, Endometrial Cancer, Breast Cancer

23-044          Phase II

First-in-Human Study of STX-478, a Mutant-Selective PI3Ka Inhibitor as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumor

  • Breast Cancer

22-256          Phase I

First-in-Human, Escalating Oral Dose Study of RGT-419B Given Alone and with Endocrine Therapy in Subjects with Hormone Receptor Positive, Human Epidermal Growth Factor Receptor 2 Negative Advanced/Metastatic Breast Cancer

  • Lung Cancer, Breast Cancer, Brain Tumors, Metastatic

19-553          Phase II

Genomically-Guided Treatment Trial in Brain Metastases

  • Breast Cancer, Colorectal Cancer, Head and Neck Cancer, Lung Cancer, Melanoma, Bladder Cancer

22-405          Phase II

Phase 1/2 Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants with Advanced Solid Tumors

  • Breast Cancer

14-056-RISK          Phase II

Phase II Double-Blind Randomized Controlled Trial of Naltrexone for Treatment-Emergent Fatigue in Patients Receiving Radiation Therapy for Breast Cancer

Showing 21 - 30 of 32 results