Basic research under way at the Center for Cancer Research, within the Massachusetts General Hospital Cancer Center, is focused on identifying novel genes that are central to both normal development and cancer, exploring the fundamental pathways that are critically altered in tumor cells, and taking this knowledge from the bench to the bedside.

The Center for Cancer Research draws from a multidisciplinary faculty within the Massachusetts General Hospital Cancer Center, dedicated to basic research on cancer. Laboratory interests range from developmental biology and the study of model organisms, to mouse and human cancer genetics, signal transduction and experimental cancer therapeutics, cell cycle checkpoints and the cellular response to DNA damage, gene expression and transcriptional regulation, and genomic approaches to the study of cancer.

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