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Learn About Adrenocortical Cancer
Written by NCI/PDQ®

Source: Cancer Resource Room

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What is cancer of the adrenal cortex?
Adrenal Gland, Massachusetts General Hospital Cancer Center, Boston, MACancer of the adrenal cortex, a rare cancer, is a disease in which cancer (malignant) cells are found in the adrenal cortex, which is the outside layer of the adrenal gland. Cancer of the adrenal cortex is also called adrenocortical carcinoma. There are two adrenal glands, one above each kidney in the back of the upper abdomen. The adrenal glands are also called the suprarenal glands. The inside layer of the adrenal gland is called the adrenal medulla. Cancer that starts in the adrenal medulla is called pheochromocytoma.

The cells in the adrenal cortex make important hormones that help the body work properly. When cells in the adrenal cortex become cancerous, they may make too much of one or more hormones, which can cause symptoms such as high blood pressure, weakening of the bones, or diabetes. If male or female hormones are affected, the body may go through changes such as a deepening of the voice, growing hair on the face, swelling of the sex organs, or swelling of the breasts. Cancers that make hormones are called functioning tumors. Many cancers of the adrenal cortex do not make extra hormones and are called nonfunctioning tumors.

What are the symptoms of cancer of the adrenal cortex?
A doctor should be seen if the following symptoms appear and won’t go away:

  • pain in the abdomen,
  • loss of weight without dieting, or
    weakness

If there is a functioning tumor, there may be symptoms or signs caused by too many hormones.

How is cancer of the adrenal cortex diagnosed?
If there are symptoms, a doctor will order blood and urine tests to see whether the amounts of hormones in the body are normal. A doctor may also order a computed tomography scan of your abdomen, a special x-ray that uses a computer to make a picture of the inside of the abdomen. Other special x-rays may also be done to tell what kind of tumor is present.

The chance of recovery (prognosis) depends on how far the cancer has spread (stage) and on whether a doctor was able to surgically remove all of the cancer.

To read more about Adrenocortical Cancer >>>

Support & Education Programs

We know that being diagnosed with cancer can be stressful for you and your family. We offer a variety of cancer support services to help patients and families gain the support and information they will need to meet the challenges ahead.

To find free education and support workshops plus wellness services, please view the HOPES calendar.

Read the most recent SUPPORT publication, a resource written by patients and families for patients and families >>>

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